Target Name: WDR70
NCBI ID: G55100
Review Report on WDR70 Target / Biomarker Content of Review Report on WDR70 Target / Biomarker
WDR70
Other Name(s): WD repeat-containing protein 70 | WD repeat domain 70 | WDR70 variant 1 | WD repeat-containing protein 70 (isoform 1) | WD repeat domain 70, transcript variant 1 | WDR70_HUMAN

WDR70: A Potential Drug Target and Biomarker

WDR70 (Wastage-associated protein 70) is a heat shock protein (HSP) that is expressed in various tissues and cells of the human body. It is a member of the HSP70 family, which is known for their ability to withstand and recover from thermal stress, including stress caused by exercise, UV radiation, and other environmental factors. WDR70 has been shown to play a role in various cellular processes, including cell survival, apoptosis, and inflammation.

Drug Target Potential

WDR70 has been identified as a potential drug target due to its unique structure and its ability to interact with small molecules, which can trigger various cellular responses. One of the most promising aspects of WDR70 as a drug target is its ability to modulate the expression of genes involved in cell survival and apoptosis, which can lead to therapeutic benefits in diseases such as cancer, neurodegenerative disorders, and chronic obstructive pulmonary disease (COPD).

For example, studies have shown that inhibiting WDR70 can lead to increased cell apoptosis in cancer cells, which can be a potential mechanism for cancer therapy. Additionally, WDR70 has been shown to be involved in the regulation of cell cycle progression, which can be a potential target for therapies aimed at slowing down the progression of cancer or neurodegenerative disorders.

Biomarker Potential

WDR70 has also been identified as a potential biomarker for various diseases, including cancer, neurodegenerative disorders, and COPD. Its expression has been shown to be affected by a variety of factors, including temperature, stress, and exposure to environmental toxins. This suggests that WDR70 may be a useful biomarker for tracking the effects of therapeutic interventions on these diseases.

In addition, the ability of WDR70 to interact with small molecules has been shown to be involved in the regulation of various cellular processes, including inflammation and fibrosis. This suggests that WDR70 may be a potential target for therapies aimed at reducing inflammation and promoting wound healing, which can be beneficial in diseases such as rheumatoid arthritis and chronic obstructive pulmonary disease.

Conclusion

WDR70 is a unique protein that has been shown to play a role in various cellular processes in the human body. Its potential as a drug target and biomarker makes it an attractive target for further research and development. As research continues to uncover the functions of WDR70 and its potential as a therapeutic intervention, it is likely that new treatments for a variety of diseases will be discovered.

Protein Name: WD Repeat Domain 70

The "WDR70 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WDR70 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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