Target Name: IMP3
NCBI ID: G55272
Review Report on IMP3 Target / Biomarker Content of Review Report on IMP3 Target / Biomarker
IMP3
Other Name(s): C15orf12 | BRMS2 | MRPS4 | DKFZp586L0118 | U3 snoRNP protein IMP3 | IMP3, U3 small nucleolar ribonucleoprotein, homolog | IMP U3 small nucleolar ribonucleoprotein 3 | FLJ10968 | U3 snoRNP protein 3 homolog | IMP3_HUMAN | U3 small nucleolar ribonucleoprotein protein IMP3

IMP3: A Protein Involved in Cell Adhesion, Migration and Invasion

IMP3 (Integrin-like protein 3) is a protein that is expressed in various tissues throughout the body. It is a member of the integrin family, which is a group of transmembrane proteins that play a critical role in cell-cell and cell-extracellular matrix interactions. IMP3 has been shown to be involved in several cellular processes, including cell adhesion, migration, and invasion.

IMP3 is a 21-kDa protein that is expressed in a variety of tissues, including the brain, heart, liver, and pancreas. It is predominantly expressed in the liver, where it is involved in the production of extracellular matrix (ECM) components such as collagen and laminin.

IMP3 has been shown to be involved in several signaling pathways that are important for cell behavior and development. One of the most well-studied functions of IMP3 is its role in cell adhesion. IMP3 is a critical regulator of cell-cell adhesion, and it has been shown to play a key role in the regulation of cell-cell interactions during various stages of development, including embryonic development and tissue repair.

IMP3 is also involved in the regulation of cell migration and invasion. It has been shown to play a critical role in the migration of cancer cells to new tumors, as well as in the regulation of normal cell migration during development and wound healing.

IMP3 is also involved in the regulation of inflammation and immune responses. It has been shown to play a critical role in the regulation of inflammation and immune cell responses, as well as in the regulation of inflammation-induced pain.

In addition to its role in cell biology, IMP3 is also a potential drug target. Several studies have shown that IMP3 can be targeted by small molecules, including inhibitors of tyrosine kinase activity and inhibitors of the production of ECM components. These small molecules have been shown to have a variety of different effects on cellular behavior, including the regulation of cell adhesion, migration, and invasion.

Overall, IMP3 is a protein that is involved in a variety of cellular processes that are important for normal cellular function and development. Its role in these processes makes it an attractive target for the development of new drugs for a variety of diseases. Further research is needed to fully understand the functions of IMP3 and its potential as a drug target.

Protein Name: IMP U3 Small Nucleolar Ribonucleoprotein 3

Functions: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)

The "IMP3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IMP3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

IMP4 | IMPA1 | IMPA1P1 | IMPA2 | IMPACT | IMPDH1 | IMPDH1P10 | IMPDH1P6 | IMPDH2 | IMPG1 | IMPG2 | INA | INAFM1 | INAFM2 | INAVA | INCA1 | INCENP | INE1 | INE2 | INF2 | ING1 | ING2 | ING2-DT | ING3 | ING4 | ING5 | INGX | INHA | INHBA | INHBA-AS1 | INHBB | INHBC | INHBE | INHCAP | Inhibitor of Apoptosis Proteins (IAPs) | Inhibitory kappaB Kinase (IKK) | INIP | INKA1 | INKA2 | INKA2-AS1 | INMT | INMT-MINDY4 | Innate Repair Receptor (IRR) | INO80 | INO80 complex | INO80B | INO80B-WBP1 | INO80C | INO80D | INO80E | Inositol 1,4,5-Trisphosphate Receptor (InsP3R) | Inositol hexakisphosphate kinase | Inositol Monophosphatase | INPP1 | INPP4A | INPP4B | INPP5A | INPP5B | INPP5D | INPP5E | INPP5F | INPP5J | INPP5K | INPPL1 | INS | INS-IGF2 | INSC | INSIG1 | INSIG2 | INSL3 | INSL4 | INSL5 | INSL6 | INSM1 | INSM2 | INSR | INSRR | Insulin-like growth factor | Insulin-like growth factor 2 mRNA binding protein | Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2) | Insulin-like growth factor-binding protein | INSYN1 | INSYN2A | INSYN2B | Integrator complex | Integrin alpha1beta1 (VLA-1) receptor | Integrin alpha2beta1 (VLA-2) receptor | Integrin alpha2beta3 Receptor | Integrin alpha3beta1 receptor | Integrin alpha4beta1 (VLA-4) receptor | Integrin alpha4beta7 (LPAM-1) receptor | Integrin alpha5beta1 (VLA-5) receptor | Integrin alpha5beta3 receptor | Integrin alpha6beta1 Receptor | Integrin alpha6beta4 receptor | Integrin alpha7beta1 Receptor | Integrin alpha9beta1 receptor | Integrin alphaEbeta7 receptor | Integrin alphaLbeta2 (LFA-1) receptor | Integrin alphaMbeta2 (MAC-1) Receptor