Target Name: PAPOLB
NCBI ID: G56903
Review Report on PAPOLB Target / Biomarker Content of Review Report on PAPOLB Target / Biomarker
PAPOLB
Other Name(s): Poly(A) polymerase beta | TPAP | PAPT | PAPOB_HUMAN | polynucleotide adenylyltransferase beta | testis-specific poly(A) polymerase | PAP-beta | poly(A) polymerase beta | poly(A) polymerase beta (testis specific) | Testis-specific poly(A) polymerase | Polynucleotide adenylyltransferase beta

PAPOLB: A Key Enzyme in Gene Expression and DNA Replication

Poly(A) polymerase (PAPOLB) is a enzyme that plays a crucial role in the regulation of gene expression and DNA replication in eukaryotic cells. It is a key enzyme in the polymerase chain, which is responsible for producing the long double-stranded DNA that serves as the template for gene expression. PAPOLB is a 25 kDa protein that consists of 115 amino acid residues. It has a significant role in the regulation of gene expression and DNA replication in various organisms, including humans.

PAPOLB is a transcriptional regulator that is involved in the regulation of gene expression by binding to specific DNA sequences. It is a key enzyme in the polymerase chain, which is responsible for producing the long double-stranded DNA that serves as the template for gene expression. PAPOLB uses a specific template to produce a specific output, which is composed of alternating periods of 5' and 3' ends. This allows for precise regulation of gene expression and allows the cell to maintain a stable level of genetic diversity.

PAPOLB is also involved in DNA replication. It is a key enzyme in the DNA replication machinery, which is responsible for producing two new double-stranded DNA molecules in the cell after DNA replication has occurred. PAPOLB uses a specific template to produce a specific output, which is composed of alternating periods of 5' and 3' ends. This allows for precise regulation of DNA replication and ensures that the cell has a full set of genetic material.

PAPOLB is a protein that is expressed in various cell types, including muscle cells, nerve cells, and epithelial cells. It is also expressed in various tissues, including the brain, heart, and liver. PAPOLB is involved in the regulation of gene expression and DNA replication in various organisms, including humans.

PAPOLB is a potential drug target and may be used as a biomarker for various diseases. For example, PAPOLB is involved in the regulation of gene expression and DNA replication, which is implicated in the development and progression of many diseases, including cancer, neurodegenerative diseases, and genetic disorders.

PAPOLB is also a potential biomarker for certain diseases, including cancer. Cancer is a disease that is characterized by the uncontrolled growth and proliferation of cells. The regulation of gene expression and DNA replication by PAPOLB is implicated in the development and progression of cancer. Therefore, PAPOLB may be used as a biomarker for cancer diagnosis and treatment.

PAPOLB is also a potential drug target for neurodegenerative diseases. Neurodegenerative diseases are a group of diseases that are characterized by the progressive loss of brain cells and the development of neurofibrillary tangles. The regulation of gene expression and DNA replication by PAPOLB is implicated in the development and progression of neurodegenerative diseases. Therefore, PAPOLB may be used as a drug target for neurodegenerative diseases.

In conclusion, PAPOLB is a protein that is involved in the regulation of gene expression and DNA replication in various organisms, including humans. It is a key enzyme in the polymerase chain and plays a crucial role in the regulation of gene expression and DNA replication. PAPOLB is also involved in the regulation of DNA replication and may be a potential drug target for various diseases, including cancer, neurodegenerative diseases, and genetic disorders. Further research is needed to fully understand the role of PAPOLB in the regulation of gene expression and DNA replication.

Protein Name: Poly(A) Polymerase Beta

The "PAPOLB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PAPOLB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PAPOLG | PAPPA | PAPPA-AS1 | PAPPA-AS2 | PAPPA2 | PAPSS1 | PAPSS2 | PAQR3 | PAQR4 | PAQR5 | PAQR6 | PAQR7 | PAQR8 | PAQR9 | PAR Receptor | PAR-3-PAR-6B-PRKCI complex | Parathyroid Hormone Receptors (PTHR) | PARD3 | PARD3B | PARD6A | PARD6B | PARD6G | PARD6G-AS1 | PARG | PARGP1 | PARK7 | PARL | PARM1 | PARM1-AS1 | PARN | PARP1 | PARP10 | PARP11 | PARP12 | PARP14 | PARP15 | PARP16 | PARP2 | PARP3 | PARP4 | PARP6 | PARP8 | PARP9 | PARPBP | PARS2 | PART1 | PARTICL | PARVA | PARVB | PARVG | Parvovirus initiator complex | PASD1 | PASK | Patatin-like phospholipase domain-containing protein | PATE1 | PATE2 | PATE3 | PATE4 | PATJ | PATL1 | PATL2 | PATZ1 | PAUPAR | PAWR | PAX1 | PAX2 | PAX3 | PAX4 | PAX5 | PAX6 | PAX6-AS1 | PAX7 | PAX8 | PAX8-AS1 | PAX9 | PAXBP1 | PAXBP1-AS1 | PAXIP1 | PAXIP1-AS2 | PAXIP1-DT | PAXX | PBDC1 | PBK | PBLD | PBOV1 | PBRM1 | PBX1 | PBX2 | PBX3 | PBX3-DT | PBX4 | PBXIP1 | PC | PCA3 | PCAF complex | PCARE | PCAT1 | PCAT14 | PCAT18 | PCAT19