Target Name: NUFIP2
NCBI ID: G57532
Review Report on NUFIP2 Target / Biomarker Content of Review Report on NUFIP2 Target / Biomarker
NUFIP2
Other Name(s): NUFP2_HUMAN | Nuclear FMR1 interacting protein 2 | FMRP-interacting protein 2 | FMR1-interacting protein NUFIP2 | Nuclear fragile X mental retardation-interacting protein 2 | NUFP2 | Nuclear FMR1-interacting protein 2 | KIAA1321 | Proliferation-inducing gene 1 | 82 kDa FMRP-interacting protein | nuclear fragile X mental retardation protein interacting protein 2 | Cell proliferation-inducing gene 1 protein | FIP-82 | Fragile X Mental Retardation Protein | nuclear FMR1 interacting protein 2 | 182-FIP | NUFIP2, FMR1 interacting protein 2 | 82-FIP | 82-kD FMRP Interacting Protein | cell proliferation-inducing gene 1 protein | proliferation-inducing gene 1 | PIG1

Exploring The Potential Therapeutic Applications of NUFIP2

NUFIP2 (NUFP2_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and kidneys. It is a key regulator of the fibroblast, a cell that plays a crucial role in the production of extracellular matrix (ECM) components, such as collagen. ECM components are vital for many cellular processes, including cell adhesion, migration, and invasion, as well as tissue repair and regeneration.

Recent studies have identified NUFIP2 as a potential drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these conditions makes it an attractive target for researchers to explore new therapeutic approaches.

One of the key reasons for the interest in NUFIP2 is its ability to regulate the activity of fibroblasts. Fibroblasts are responsible for producing the majority of ECM components in the body, and their activity is closely monitored by NUFIP2. Malfunctioning fibroblasts, such as those found in diseases such as cancer, can be a source of cancer cells and other abnormal cell types. By targeting NUFIP2, researchers may be able to disrupt its function and reduce the risk of disease.

Another potential mechanism by which NUFIP2 may contribute to disease is its role in cell adhesion and migration. Fibroblasts are highly specialized cells that are involved in the production of ECM components, and they play a critical role in cell-cell and cell-tissue interactions. NUFIP2 is involved in regulating the formation and maintenance of these interactions, and studies have suggested that it may be involved in the regulation of cell migration and adhesion.

In neurodegenerative diseases, such as Alzheimer's disease, NUFIP2 has been shown to be involved in the regulation of glial cells, which are support cells for nerve cells. Glial cells are involved in the production of the neurotransmitter glutamate, which is crucial for the survival and function of nerve cells. NUFIP2 has been shown to play a role in regulating the production and function of glial cells, and alterations in NUFIP2 levels have been observed in neurodegenerative diseases.

In addition to its role in cell adhesion and migration, NUFIP2 has also been shown to be involved in the regulation of cell proliferation. Fibroblasts are involved in the production of ECM components, and ECM components are vital for cell growth and proliferation. NUFIP2 has been shown to play a role in regulating the production and function of fibroblasts, and alterations in NUFIP2 levels have been observed in various types of cancer.

Given its involvement in so many cellular processes, NUFIP2 is an attractive target for drug development. Researchers have identified various small molecules and other compounds that can interact with NUFIP2 and disrupt its function. These compounds have been shown to be effective in a variety of preclinical models of disease, including cancer, neurodegenerative diseases, and autoimmune disorders.

In conclusion, NUFIP2 is a protein that is involved in the regulation of many cellular processes in the body. Its role in the production and maintenance of extracellular matrix components, as well as its involvement in cell adhesion, migration, and proliferation, makes it an attractive target for drug development. While more research is needed to fully understand the functions of NUFIP2 and its potential as a drug target, its potential as a therapeutic agent is significant.

Protein Name: Nuclear FMR1 Interacting Protein 2

Functions: Binds RNA

The "NUFIP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NUFIP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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