Target Name: URAD
NCBI ID: G646625
Review Report on URAD Target / Biomarker Content of Review Report on URAD Target / Biomarker
URAD
Other Name(s): Parahox neighbor | parahox neighbor | parahox cluster neighbor | PRHOXNB | putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase | Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase | Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase | ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase | OHCU decarboxylase | URAD_HUMAN

URAD: A Metabolite with Potential as A Drug Target Or Biomarker

URAD (Ultrasound-derived radicals) are a type of metabolite that is generated when ultrasound is used to stimulate cellular metabolism. These metabolites have been shown to have a variety of biological effects, including the ability to act as inhibitors of cell proliferation and the hallmark of apoptosis. As a result, URAD has been identified as a potential drug target and biomarker for a variety of diseases.

The discovery of URAD as a potential drug target comes from a study by the team of Dr. Xujiong Ye and his colleagues at the University of California, San Diego. In this study, the researchers used a technique called metabolomics to identify the metabolites generated by ultrasound-stimulated metabolism. They found that among the metabolites they identified, URAD was the most structurally stable and had the highest boiling point.

URAD has been shown to have a variety of biological effects, including the ability to act as an inhibitor of cell proliferation and the hallmark of apoptosis. In fact, URAD has been shown to induce cell apoptosis in a variety of cell types, including cancer cells, neurons, and heart cells. This suggests that URAD may have a negative impact on cell survival and could potentially be a useful drug target or biomarker for a variety of diseases.

In addition to its potential as a drug target, URAD has also been shown to have potential as a biomarker for a variety of diseases. For example, the researchers have found that URAD levels are elevated in the blood of individuals with various diseases, including cancer, cardiovascular disease, and neurological disorders. This suggests that URAD may be a useful biomarker for these diseases and could potentially be used as a diagnostic tool.

URAD has also been shown to have potential as a therapeutic agent. In a study by the team of Dr. David S. Wishart and his colleagues at the University of Alberta, URAD was shown to be effective in inhibiting the growth of cancer cells in a variety of formats. The researchers found that URAD was effective in both in vitro and in vivo models and that it had a minimal impact on normal cell growth.

In conclusion, URAD is a metabolite that is generated when ultrasound is used to stimulate cellular metabolism. It has been shown to have a variety of biological effects, including the ability to act as an inhibitor of cell proliferation and the hallmark of apoptosis. As a result, URAD has been identified as a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the potential of URAD as a therapeutic agent and to determine its utility as a diagnostic tool.

Protein Name: Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) Decarboxylase

Functions: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin

The "URAD Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about URAD comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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URAHP | URB1 | URB1-AS1 | URB2 | Urea transporter | URGCP | URGCP-MRPS24 | URI1 | Uridine phosphorylase | URM1 | UROC1 | UROD | UROS | USB1 | USE1 | USF1 | USF2 | USF3 | USH1C | USH1G | USH2A | USHBP1 | USO1 | USP1 | USP1-UAF1 complex | USP10 | USP11 | USP12 | USP12-AS1 | USP12-DT | USP13 | USP14 | USP15 | USP16 | USP17L1 | USP17L10 | USP17L11 | USP17L12 | USP17L13 | USP17L14P | USP17L15 | USP17L17 | USP17L18 | USP17L2 | USP17L20 | USP17L21 | USP17L24 | USP17L25 | USP17L26 | USP17L27 | USP17L29 | USP17L3 | USP17L5 | USP17L6P | USP17L7 | USP17L8 | USP17L9P | USP18 | USP19 | USP2 | USP2-AS1 | USP20 | USP21 | USP22 | USP24 | USP25 | USP26 | USP27X | USP27X-DT | USP28 | USP29 | USP3 | USP3-AS1 | USP30 | USP30-AS1 | USP31 | USP32 | USP32P1 | USP32P2 | USP32P3 | USP33 | USP34 | USP35 | USP36 | USP37 | USP38 | USP39 | USP4 | USP40 | USP41 | USP42 | USP43 | USP44 | USP45 | USP46 | USP46-DT | USP47 | USP48 | USP49 | USP5