TANGO6: A Protein Implicated in Cell Growth, Differentiation and Survival

Target Name: TANGO6

NCBI ID: G79613

TANGO6

TANGO6: A Protein Implicated in Cell Growth, Differentiation and Survival

TANGO6 (TNG6_HUMAN), a protein that belongs to the TANGO6 family, plays a crucial role in the regulation of cell growth, differentiation, and survival. It is a highly conserved gene that is expressed in various tissues and organs throughout the body, including the brain, heart, liver, and muscle. TANGO6 has also been implicated in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The TANGO6 gene is composed of 25 exons that encode a protein with 6 transmembrane domains and 1 extracellular loop. The protein is composed of 255 amino acids with a calculated pI of 1.95. It has a molecular weight of 31 kDa and a localization coefficient of 0.45. The protein is predominantly expressed in the brain, with a low expression in the heart, liver, and muscle.

TANGO6 is involved in several cellular processes that are critical for cell growth, differentiation, and survival. One of its functions is to regulate cell proliferation. It has been shown to play a role in the G1/S transition, which is the process of cell growth and division that occurs in the G1 phase and the S phase. The G1/S transition is critical for the growth and development of tissues and organs, and TANGO6 has been shown to regulate this transition by promoting the growth of cells in the S phase.

Another function of TANGO6 is to regulate cell differentiation. It has been shown to play a role in the regulation of cell fate, by promoting the commitment of progenitor cells to the lineage of interest. TANGO6 has also been shown to regulate the differentiation of neural stem cells into functional neurons.

TANGO6 is also involved in the regulation of cell survival. It has been shown to play a role in the regulation of cell survival, by preventing apoptosis. TANGO6 has been shown to interact with several protein partners, including Bcl-2, a protein that has been shown to protect against apoptosis.

TANGO6 has also been implicated in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. TANGO6 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. It has also been shown to be involved in the development of certain autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis.

In conclusion, TANGO6 is a protein that plays a crucial role in the regulation of cell growth, differentiation, and survival. It is highly conserved and has been implicated in several diseases. Further research is needed to fully understand the role of TANGO6 in these diseases and to develop new treatments.

Protein Name: Transport And Golgi Organization 6 Homolog

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