Target Name: UQCRFS1P1
NCBI ID: G100128525
Review Report on UQCRFS1P1 Target / Biomarker Content of Review Report on UQCRFS1P1 Target / Biomarker
Other Name(s): Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 1 | UQCRFSL1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 1

Introduction to UQCRFS1P1, A Potential Drug Target

UQCRFS1P1, also known as Ubiquinol-cytochrome c reductase Rieske iron-sulfur polypeptide 1 pseudogene 1, is an emerging drug target and biomarker that holds promising potential in the field of biomedical research. This article aims to shed light on the significance of UQCRFS1P1, its role in various diseases, the current research being conducted, and its potential applications in diagnosis, prognosis, and treatment.

UQCRFS1P1: An Overview

UQCRFS1P1 is a pseudogene, which means it is a non-functional or incomplete copy of a functional gene. It is located on human chromosome 19q13.2. Initially considered a non-coding RNA, recent studies have shown that it does play a functional role in certain biological processes.

Association with Diseases

Research has demonstrated the involvement of UQCRFS1P1 in the pathogenesis of several diseases. For instance, studies have highlighted its association with various cancers, including lung, breast, and ovarian. Increased expression of UQCRFS1P1 has been observed in cancer tissues, suggesting its potential role as an oncogene or as a biomarker for cancer diagnosis and progression.

Moreover, UQCRFS1P1 has been implicated in neurodegenerative diseases such as Alzheimer's and Parkinson's. In these conditions, aberrant expression of UQCRFS1P1 has been linked to mitochondrial dysfunction, oxidative stress, and apoptosis, all of which play critical roles in the progression of these diseases.

The Role of UQCRFS1P1 in Physiology

Despite being a pseudogene, recent studies have unveiled the functional aspects of UQCRFS1P1. It has been found to regulate the expression of various coding genes involved in critical physiological processes. For instance, UQCRFS1P1 has been shown to influence the expression of genes related to energy metabolism, cell cycle regulation, and mitochondrial function. Understanding its regulatory role in these processes may unravel new therapeutic strategies for various diseases.

Utilizing UQCRFS1P1 as a Biomarker

The unique expression pattern of UQCRFS1P1 in numerous diseases renders it a promising biomarker candidate. Several studies have demonstrated the potential of UQCRFS1P1 as a diagnostic and prognostic marker for various cancers. Its elevated expression in the early stages of tumorigenesis may contribute to its potential as an early detection tool. Furthermore, monitoring UQCRFS1P1 levels during treatment could provide valuable insights into the response and progression of the disease.

Targeting UQCRFS1P1 for Therapeutic Intervention

The functional role of UQCRFS1P1 in disease pathogenesis opens up new possibilities for therapeutic interventions. Strategies aimed at modulating its expression or activity could have significant implications for the treatment of diseases such as cancer and neurodegenerative disorders. Targeted therapies could involve small molecule inhibitors, antisense oligonucleotides, or gene editing techniques to regulate UQCRFS1P1 expression and mitigate its pathological effects.

Current Research and Future Directions

Researchers are actively investigating the molecular mechanisms underlying the involvement of UQCRFS1P1 in various diseases. These studies focus on understanding its regulatory functions and the signaling pathways it modulates. By unraveling the complex interactions involving UQCRFS1P1, this research could potentially lead to the development of novel diagnostic tools and therapeutic strategies.

In the future, the clinical utility of UQCRFS1P1 in personalized medicine could be explored. By analyzing UQCRFS1P1 expression levels in individual patients, healthcare providers may be able to tailor treatment strategies based on the patient's genetic profile and UQCRFS1P1-mediated disease progression. This could revolutionize the way diseases are diagnosed and treated, improving patient outcomes and overall healthcare efficiency.


UQCRFS1P1, once dismissed as a pseudogene with no functional significance, has emerged as a crucial target for disease research. Its association with various diseases, its role in physiological processes, and its potential as a biomarker and therapeutic target highlight its immense potential in the field of biomedical research. As researchers continue to unravel the complexities surrounding UQCRFS1P1, it is hoped that this knowledge will translate into effective diagnostic and therapeutic interventions, ultimately improving patient care and outcomes.

Protein Name: Ubiquinol-cytochrome C Reductase, Rieske Iron-sulfur Polypeptide 1 Pseudogene 1

The "UQCRFS1P1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UQCRFS1P1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at

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