PHC3: A Promising Drug Target and Biomarker (G80012)

Target Name: PHC3

NCBI ID: G80012

PHC3

PHC3: A Promising Drug Target and Biomarker

PHC3, short for phosphatidylcholine, is a drug target and biomarker that has been identified by researchers for its role in the development and progression of various diseases, including cancer. The molecule is derived from the phospholipid class of biomarkers, which are essential for cellular signaling and membrane structure.

PHC3 has been shown to play a crucial role in the regulation of cellular signaling pathways, particularly in the context of cell-cell adhesion and migration. It has been shown to promote the formation of tight junctions, which are critical for maintaining tissue structure and function, and has been shown to inhibit the formation of tight junctions in the brain, leading to changes in neural network architecture and function.

PHC3 has also been shown to play a role in the regulation of angiogenesis, the process by which new blood vessels are formed. It has been shown to promote the formation of new blood vessels in wound healing, and has been shown to contribute to the development of atherosclerosis, a condition in which plaque builds up in the arteries and can cause cardiovascular disease.

In addition to its role in cellular signaling and angiogenesis, PHC3 has also been shown to play a role in the regulation of inflammation. It has been shown to promote the production of pro-inflammatory cytokines, such as TNF-alpha and IL-8, and has been shown to contribute to the regulation of the immune response.

These findings suggest that PHC3 is a promising drug target and biomarker for the treatment of a wide range of diseases, including cancer, neurodegenerative diseases, and cardiovascular disease. Further research is needed to fully understand the molecular mechanisms underlying PHC3's role in these diseases and to develop effective treatments.

Protein Name: Polyhomeotic Homolog 3

Functions: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility

The "PHC3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHC3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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