PHEX-AS1: A Potential Drug Target and Biomarker (G100873942)

Target Name: PHEX-AS1

NCBI ID: G100873942

PHEX-AS1

Other Name(s): PHEX antisense RNA 1

PHEX-AS1: A Potential Drug Target and Biomarker

PHEX-AS1 is a protein that is expressed in various tissues of the body, including the lungs, heart, kidneys, and intestines. It is a member of the PHEX gene family, which encodes a superfamily of cytoplasmic pH sensors and transporters. These proteins are involved in the regulation of intracellular pH (pH) levels, which is critical for various cellular processes. One of the PHEX genes, PHEX-AS1, has been identified as a potential drug target and biomarker for various diseases, including cancer, respiratory diseases, and neurodegenerative disorders.

The PHEX gene family has been identified in various species, including humans, and is characterized by the presence of a specific C-terminus that contains a putative cytoplasmic pH sensor. This sensor is responsible for detecting changes in pH levels within the cytoplasm and transmitting this information to the cell surface. The PHEX gene family has been shown to be involved in the regulation of various cellular processes, including cell signaling, DNA replication, and stress response.

PHEX-AS1 is a splicing variant of the PHEX gene that has been shown to be expressed in various tissues of the body. It is highly expressed in the lungs, where it is involved in the regulation of pH levels in the airways and the blood vessels of the lungs. PHEX-AS1 has also been shown to be involved in the regulation of pH levels in the heart, kidneys, and intestines, where it is responsible for maintaining the proper pH balance within these organs.

In addition to its role in cell signaling and pH regulation, PHEX-AS1 has also been shown to play a role in the development and progression of various diseases. For example, PHEX-AS1 has been shown to be involved in the development of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. It has also been shown to be involved in the development of cancer, including breast and ovarian cancer.

As a potential drug target, PHEX-AS1 has been the focus of research in the field of cancer. Studies have shown that PHEX-AS1 can be overexpressed in various cancer types, including breast, ovarian, and prostate cancer. This overexpression can lead to the formation of PHEX-AS1-positive cancer cells, which may contribute to the development and progression of these diseases.

In addition to its potential as a drug target, PHEX-AS1 has also been identified as a potential biomarker for various diseases. The detection of PHEX-AS1 expression in cancer cells and otherPHEX-AS1-positive tissues may be a useful diagnostic tool for the diagnosis and evaluation of these diseases. Additionally, the regulation of PHP levels in PHEX-AS1-positive cancer cells may be a useful target for the development of new cancer therapies.

In conclusion, PHEX-AS1 is a protein that is involved in the regulation of various cellular processes and has been identified as a potential drug target and biomarker for various diseases. Further research is needed to fully understand its role in the development and progression of these diseases, as well as its potential as a drug and biomarker.

Protein Name: PHEX Antisense RNA 1

The "PHEX-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHEX-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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