Target Name: NKAIN2
NCBI ID: G154215
Review Report on NKAIN2 Target / Biomarker Content of Review Report on NKAIN2 Target / Biomarker
NKAIN2
Other Name(s): Sodium/potassium transporting ATPase interacting 2, transcript variant 1 | sodium/potassium transporting ATPase interacting 2 | T-cell lymphoma breakpoint-associated target protein 1 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 (isoform 1) | FAM77B | Na+/K+ transporting ATPase interacting 2 | TCBA | TCBA1 | NKAIP2 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 | Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2 | NKAI2_HUMAN | Protein FAM77B | MGC41924 | NKAIN2 variant 1

NKAIN2: A Potential Drug Target and Biomarker for Sodium and Potassium Transport

Abstract:

NKAIN2 (Sodium/Potassium Transporting ATPase Interacting 2), transcript variant 1, is a gene that encodes a protein involved in the transport of sodium and potassium ions in cells. The encoded protein, NKAIN2, has been shown to play a crucial role in the regulation of intracellular sodium and potassium levels, which are essential for various physiological processes, including muscle and nerve function, as well as signaling pathways. The potential drug targets and biomarkers associated with NKAIN2 have been identified, and the potential clinical applications of targeting NKAIN2 are discussed.

Introduction:

Sodium and potassium ions are essential nutrients for maintaining the physiological functions of the human body. They play a critical role in muscle and nerve function, as well as signaling pathways. The regulation of sodium and potassium ions is crucial for maintaining the resting membrane potential of cells, which is essential for the proper functioning of various physiological processes. The sodium/potassium transporting ATPase interacting 2 (NKAIN2) is a protein that plays a crucial role in the regulation of intracellular sodium and potassium levels.

NKAIN2 is a member of the ATPase interacting protein (AIP) family, which includes proteins that play a critical role in the regulation of intracellular signaling pathways. NKAIN2 is expressed in various tissues and cell types, including muscle, nerve, and heart. It is involved in the regulation of sodium and potassium ions, which are essential for the proper functioning of these tissues.

The potential drug targets and biomarkers associated with NKAIN2 have been identified, and the potential clinical applications of targeting NKAIN2 are discussed.

Potential Drug Targets and Biomarkers:

NKAIN2 has been shown to play a crucial role in the regulation of intracellular sodium and potassium levels. The regulation of these ions is essential for various physiological processes, including muscle and nerve function, as well as signaling pathways. The potential drug targets associated with NKAIN2 are summarized in Table 1.

Table 1: Potential Drug Targets and Biomarkers associated with NKAIN2

* BCMA (Bcr-Abl-associated protein kinase)
* CIK (Ca2+-sensitive adapter protein)
*GLUT (GLUT4)
* HSP70 (Hemoglobin subunit 70)
*Pore

These drug targets are associated with NKAIN2 because of its role in the regulation of sodium and potassium ions. Blockade of these drug targets may lead to the disruption of NKAIN2-mediated intracellular sodium and potassium regulation, which may have potential clinical applications.

In addition to its role in the regulation of intracellular sodium and potassium ions, NKAIN2 has also been shown to play a critical role in the regulation of intracellular signaling pathways. The NKAIN2-mediated intracellular signaling pathway has been implicated in various physiological processes, including cell growth, apoptosis, and neurotransmission.

The potential biomarkers associated with NKAIN2 are summarized in Table 2.

Table 2: Potential Biomarkers associated with NKAIN2

*Cell count
*Intracellular sodium levels
* Intracellular potassium levels
*Signal transduction

These biomarkers are associated with NKAIN2 because of its role in the regulation of intracellular sodium and potassium ions. The disruption of NKAIN2-mediated intracellular sodium and potassium regulation may be associated with various physiological

Protein Name: Sodium/potassium Transporting ATPase Interacting 2

The "NKAIN2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NKAIN2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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NKAIN3 | NKAIN4 | NKAP | NKAPD1 | NKAPL | NKAPP1 | NKD1 | NKD2 | NKG7 | NKILA | NKIRAS1 | NKIRAS2 | NKPD1 | NKRF | NKTR | NKX1-1 | NKX1-2 | NKX2-1 | NKX2-1-AS1 | NKX2-2 | NKX2-3 | NKX2-4 | NKX2-5 | NKX2-6 | NKX2-8 | NKX3-1 | NKX3-2 | NKX6-1 | NKX6-2 | NKX6-3 | NLE1 | NLGN1 | NLGN1-AS1 | NLGN2 | NLGN3 | NLGN4X | NLGN4Y | NLK | NLN | NLRC3 | NLRC4 | NLRC4 Inflammasome | NLRC5 | NLRP1 | NLRP1 Inflammasome | NLRP10 | NLRP11 | NLRP12 | NLRP13 | NLRP14 | NLRP2 | NLRP2B | NLRP3 | NLRP3 Inflammasome | NLRP3P1 | NLRP4 | NLRP5 | NLRP6 | NLRP7 | NLRP8 | NLRP9 | NLRP9P1 | NLRX1 | NMB | NMBR | NMD3 | NMDA receptor | NME1 | NME1-NME2 | NME2 | NME2P1 | NME3 | NME4 | NME5 | NME6 | NME7 | NME8 | NME9 | NMI | NMNAT1 | NMNAT2 | NMNAT3 | NMRAL1 | NMRAL2P | NMRK1 | NMRK2 | NMS | NMT1 | NMT2 | NMTRQ-TTG10-1 | NMTRQ-TTG12-1 | NMTRV-TAC1-1 | NMU | NMUR1 | NMUR2 | NNAT | NNMT | NNT | NNT-AS1 | NOA1