NME7: A Protein Involved in Cell Signaling and Inflammation (G29922)

Target Name: NME7

NCBI ID: G29922

NME7

NME7: A Protein Involved in Cell Signaling and Inflammation

NME7 (N-Methyl-L-Threonine), also known as nm23-H7, is a protein that is expressed in various tissues and cells in the body. It is a key regulator of cell proliferation and has been implicated in a number of cellular processes, including cell growth, differentiation, and inflammation.

One of the key functions of NME7 is its role in cell signaling. It is a scaffold protein that can interact with various signaling molecules, including TGF-β, NF-kappa-B, and p53. These molecules are involved in regulating cellular processes such as cell growth, differentiation, and apoptosis.

NME7 has also been shown to play a role in the regulation of inflammation. It has been shown to promote the production of pro-inflammatory cytokines, such as TNF-伪 and IL-1尾, and has been shown to contribute to the development of inflammatory diseases, such as rheumatoid arthritis and atherosclerosis.

In addition to its role in cell signaling and inflammation, NME7 has also been shown to be involved in the regulation of cellular processes that are important for tissue repair and regeneration. It has been shown to promote the proliferation and migration of progenitor cells, which are important for the development and repair of tissues.

Given its involvement in so many cellular processes, NME7 is a promising drug target. Researchers have identified several potential drugs that can inhibit NME7 activity, and these drugs have been shown to have a variety of therapeutic effects, including the treatment of diseases such as cancer , autoimmune disorders, and neurodegenerative diseases.

One of the challenges in studying NME7 is its complex structure and the difficulty of predicting its function. While it is known to play a role in several cellular processes, it is not yet clear exactly how it functions and how it can be effectively targeted by drugs.

In conclusion, NME7 is a protein that has important roles in cell signaling and inflammation. Its potential as a drug target makes it an attractive target for the development of new therapies for a variety of diseases. Further research is needed to fully understand its function and develop effective treatments.

Protein Name: NME/NM23 Family Member 7

Functions: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity)

The "NME7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NME7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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