Target Name: NLRX1
NCBI ID: G79671
Review Report on NLRX1 Target / Biomarker Content of Review Report on NLRX1 Target / Biomarker
NLRX1
Other Name(s): NLRX1 variant 1 | MGC21025 | MGC131937 | nucleotide-binding oligomerization domain protein 5 | Nucleotide-binding oligomerization domain, leucine rich repeat containing X1 | FLJ21478 | NLR family member X1 | NOD9 | nucleotide-binding oligomerization domain protein 26 | NOD-like receptor X1 | CLR11.3 | DLNB26 | nucleotide-binding oligomerization domain protein 9 | Nucleotide-binding oligomerization domain protein 9 | Nucleotide-binding oligomerization domain protein 5 | Protein Caterpiller 11.3 | caterpiller protein 11.3 | nucleotide-binding oligomerization domain, leucine rich repeat containing X1 | NOD26 | Caterpiller protein 11.3 | NLR family, X1 | NOD5 | Nucleotide-binding oligomerization domain protein 26 | NLRX1_HUMAN

NLRX1: A Potential Drug Target Or Biomarker

NLRX1 (NLRX1 variant 1) is a non-coding RNA molecule that has been identified as a potential drug target or biomarker. NLRX1 is a key regulator of the cell's response to bacterial infections, and its dysfunction has been linked to a number of diseases, including bacterial infections, sepsis, and cancer.

The NLRX1 gene is located on chromosome 18 and contains 21 exons. NLRX1 has a length of approximately 290 nucleotides and is expressed in most tissues of the body. It is a RNA molecule that plays a role in the regulation of gene expression, and is involved in the control of various cellular processes, including inflammation, infection, and cellular signaling.

The functions of NLRX1 are wide-ranging and include the regulation of bacterial infections, the response to traumatic injuries, and the regulation of cancer cell growth. NLRX1 has also been shown to play a role in the regulation of inflammation and infection, and is therefore Considered a potential drug target or biomarker.

NLRX1 has also been shown to regulate the expression of genes involved in the bacterial response to an infection, including the expression of genes involved in the production of toxins and the regulation of the expression of genes involved in the immune response. regulate the expression of genes involved in the regulation of inflammation and cellular signaling.

In addition to its role in the regulation of gene expression, NLRX1 has also been shown to play a role in the regulation of cellular signaling. NLRX1 has been shown to regulate the signaling pathway involving the T-cell receptor (TCR), a key regulator of the immune response. NLRX1 has also been shown to regulate the signaling pathway involving the NF-kappa-B pathway, a key regulator of inflammation and cellular signaling.

The dysfunction of NLRX1 has been linked to a number of diseases, including bacterial infections, sepsis, and cancer. NLRX1 dysfunction has been shown to be involved in the development of sepsis, a life-threatening condition that occurs in response to an infection. NLRX1 Dysfunction has also been shown to be involved in the development of cancer, including breast cancer.

In conclusion, NLRX1 is a non-coding RNA molecule that has been identified as a potential drug target or biomarker. NLRX1 is involved in the regulation of various cellular processes, including gene expression, inflammation, and cellular signaling. Its dysfunction has been linked to a number of diseases, including bacterial infections, sepsis, and cancer. Further research is needed to fully understand the role of NLRX1 in these diseases and to develop effective treatments.

Protein Name: NLR Family Member X1

Functions: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Instead, promotes autophagy by interacting with TUFM and subsequently recruiting the autophagy-related proteins ATG5 and ATG12 (PubMed:22749352). Regulates also MAVS-dependent NLRP3 inflammasome activation to attenuate apoptosis (PubMed:27393910). Has no inhibitory function on NF-kappa-B signaling pathway, but enhances NF-kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313). Regulates viral mediated-inflammation and energy metabolism in a sex-dependent manner (By similarity). In females, prevents uncontrolled inflammation and energy metabolism and thus, may contribute to the sex differences observed in infectious and inflammatory diseases (By similarity)

The "NLRX1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NLRX1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NMB | NMBR | NMD3 | NMDA receptor | NME1 | NME1-NME2 | NME2 | NME2P1 | NME3 | NME4 | NME5 | NME6 | NME7 | NME8 | NME9 | NMI | NMNAT1 | NMNAT2 | NMNAT3 | NMRAL1 | NMRAL2P | NMRK1 | NMRK2 | NMS | NMT1 | NMT2 | NMTRQ-TTG10-1 | NMTRQ-TTG12-1 | NMTRV-TAC1-1 | NMU | NMUR1 | NMUR2 | NNAT | NNMT | NNT | NNT-AS1 | NOA1 | NOB1 | NOBOX | NOC2L | NOC2LP2 | NOC3L | NOC4L | NOCT | NOD1 | NOD2 | NODAL | NOG | NOL10 | NOL11 | NOL12 | NOL3 | NOL4 | NOL4L | NOL4L-DT | NOL6 | NOL7 | NOL8 | NOL9 | NOLC1 | NOM1 | NOMO1 | NOMO2 | NOMO3 | Non-protein coding RNA 185 | NONO | NOP10 | NOP14 | NOP14-AS1 | NOP16 | NOP2 | NOP53 | NOP56 | Nop56p-associated pre-rRNA complex | NOP58 | NOP9 | NOPCHAP1 | NORAD | NOS1 | NOS1AP | NOS2 | NOS2P1 | NOS2P2 | NOS2P3 | NOS3 | NOSIP | NOSTRIN | Notch ligands | Notch receptor | Notch Transcriptional Activation Complex | NOTCH1 | NOTCH2 | NOTCH2NLA | NOTCH2NLC | NOTCH3 | NOTCH4 | NOTO | NOTUM | NOVA1 | NOVA1-DT