NKTR: The Natural Killer Cell Triggering Receptor (NKTR)
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NKTR: The Natural Killer Cell Triggering Receptor (NKTR)
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The natural killer (NK) system is a critical immune system that helps protect the body against viruses, cancer, and other diseases. NK cells are a type of immune cell that have the ability to recognize and destroy infected or mutated cells in the body. However, there is a growing concern that NK cells can sometimes become cancerous and contribute to the development of various diseases.
One of the proteins that plays a crucial role in the NK system is the Natural Killer Cell Triggering Receptor (NKTR). The NKTR is a transmembrane protein that is expressed in the NK cells and other immune cells. It is a receptor for a variety of antigens, including viruses, bacteria, and cancer cells.
The NKTR is involved in the regulation of the NK response by allowing NK cells to recognize and respond to foreign particles in the body. It does this by engaging with the antigens and transmitting signals to the cell surface. The NKTR is also involved in the regulation of the NK cell proliferation and survival.
The discovery of the NKTR and its potential as a drug target has significant implications for the treatment of various diseases. One of the main goals of research in this field is to develop drugs that can inhibit the activity of the NKTR and enhance the activity of the NK cells. This may lead to a better understanding of the mechanisms underlying the immune system and the development of new treatments for a variety of diseases.
The NKTR is a protein that is expressed in the NK cells and other immune cells. It is involved in the regulation of the NK response by allowing NK cells to recognize and respond to foreign particles in the body.
The NKTR is composed of four transmembrane domains: an extracellular domain, a transmembrane domain, an intracellular domain, and a cytoplasmic domain. The extracellular domain is the outermost part of the NKTR and is involved in its ability to interact with other proteins. The transmembrane domain is the part of the NKTR that spans the membrane of the NK cell and is involved in the regulation of the NK response. The intracellular domain is the part of the NKTR that enters the NK cell and is involved in the regulation of the NK cell survival. The cytoplasmic domain is the part of the NKTR that is located within the cytoplasm of the NK cell and is involved in the regulation of the NK cell survival.
The NKTR is involved in the regulation of the NK response by allowing NK cells to recognize and respond to foreign particles in the body. It does this by engaging with the antigens and transmitting signals to the cell surface.
The NKTR is involved in the regulation of NK cell proliferation and survival. It does this by regulating the activity of several key signaling pathways, including the T cell signaling pathway and the PI3K/Akt signaling pathway.
The NKTR is also involved in the regulation of the NK cell cytoskeleton. It does this by regulating the activity of several proteins that are involved in the cytoskeleton, including actin and microtubules.
The NKTR is a protein that is expressed in the NK cells and other immune cells. It is involved in the regulation of the NK response by allowing NK cells to recognize and respond to foreign particles in the body.
In conclusion, the Natural Killer Cell Triggering Receptor (NKTR) is a protein that is involved in the regulation of the NK response by allowing NK cells to recognize and respond to foreign particles in the body. It is expressed in the NK cells and other immune cells and is involved in the regulation of NK cell
Protein Name: Natural Killer Cell Triggering Receptor
Functions: PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). Component of a putative tumor-recognition complex involved in the function of NK cells (PubMed:8421688)
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More Common Targets
NKX1-1 | NKX1-2 | NKX2-1 | NKX2-1-AS1 | NKX2-2 | NKX2-3 | NKX2-4 | NKX2-5 | NKX2-6 | NKX2-8 | NKX3-1 | NKX3-2 | NKX6-1 | NKX6-2 | NKX6-3 | NLE1 | NLGN1 | NLGN1-AS1 | NLGN2 | NLGN3 | NLGN4X | NLGN4Y | NLK | NLN | NLRC3 | NLRC4 | NLRC4 Inflammasome | NLRC5 | NLRP1 | NLRP1 Inflammasome | NLRP10 | NLRP11 | NLRP12 | NLRP13 | NLRP14 | NLRP2 | NLRP2B | NLRP3 | NLRP3 Inflammasome | NLRP3P1 | NLRP4 | NLRP5 | NLRP6 | NLRP7 | NLRP8 | NLRP9 | NLRP9P1 | NLRX1 | NMB | NMBR | NMD3 | NMDA receptor | NME1 | NME1-NME2 | NME2 | NME2P1 | NME3 | NME4 | NME5 | NME6 | NME7 | NME8 | NME9 | NMI | NMNAT1 | NMNAT2 | NMNAT3 | NMRAL1 | NMRAL2P | NMRK1 | NMRK2 | NMS | NMT1 | NMT2 | NMTRQ-TTG10-1 | NMTRQ-TTG12-1 | NMTRV-TAC1-1 | NMU | NMUR1 | NMUR2 | NNAT | NNMT | NNT | NNT-AS1 | NOA1 | NOB1 | NOBOX | NOC2L | NOC2LP2 | NOC3L | NOC4L | NOCT | NOD1 | NOD2 | NODAL | NOG | NOL10 | NOL11 | NOL12 | NOL3
