PLK5: A Protein Involved in Cell Signaling, Adhesion and More

Target Name: PLK5

NCBI ID: G126520

PLK5

PLK5: A Protein Involved in Cell Signaling, Adhesion and More

PLK5 (Protein-Lipid Knotase 5) is a protein that is expressed in various cell types, including neurons, muscle cells, and blood vessels. It is a serine/threonine-protein kinase, which means it catalyzes the transfer of a phosphate group from a serine or threonine residue to a protein threonine or serine residue. This process is important for many cellular processes, including cell signaling, DNA replication, and metabolism.

One of the unique features of PLK5 is its role in cell signaling. PLK5 is involved in the regulation of several intracellular signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the S/TIM signaling pathway. This means that PLK5 plays an important role in the development and maintenance of cellular signaling pathways, which are critical for many cellular processes.

Another important function of PLK5 is its role in cell adhesion. PLK5 is involved in the regulation of cell-cell adhesion, which is important for the proper functioning of tissues and organs. This is because PLK5 helps to ensure that cells stick together and form tissues, which is critical for many biological processes, including embryonic development, tissue repair, and cancer progression.

PLK5 is also involved in the regulation of cell cycle progression. This is important because the cell cycle is critical for the growth and development of cells, and it is also involved in the regulation of cell division. PLK5 helps to ensure that cells follow the correct cell cycle progression, which is important for the development and maintenance of tissues and organs.

In addition to its role in cell signaling and cell cycle regulation, PLK5 is also involved in the regulation of protein stability. This is important because the stability of proteins is critical for their function, and it is also involved in the regulation of cellular processes. PLK5 helps to ensure that certain proteins are stable and remain active, which is important for the regulation of many cellular processes.

PLK5 is also involved in the regulation of cellular signaling pathways that are important for the development and maintenance of tissues and organs. This is important because these signaling pathways are critical for the development and maintenance of tissues and organs, and they are also involved in the regulation of many cellular processes. PLK5 helps to ensure that these signaling pathways are properly regulated, which is important for the development and maintenance of tissues and organs.

In conclusion, PLK5 is a protein that is involved in several important cellular processes, including cell signaling, cell adhesion, cell cycle progression, protein stability, and cellular signaling pathways. As a result, PLK5 is an attractive drug target for researchers who are interested in the development of new treatments for a variety of diseases. By targeting PLK5, researchers may be able to develop new treatments for conditions such as cancer, neurodegenerative diseases, and cardiovascular diseases. Additionally, PLK5 may also be used as a biomarker for the diagnosis and monitoring of these diseases.

Protein Name: Polo Like Kinase 5 (inactive)

Functions: Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation

The "PLK5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLK5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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