MB21D2: A Potential Drug Target and Biomarker (G151963)

Target Name: MB21D2

NCBI ID: G151963

MB21D2

MB21D2: A Potential Drug Target and Biomarker

Introduction

MB21D2 is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug or biomarker has led to a significant amount of interest in the field.

Structure and Function

MB21D2 is a protein that is expressed in a variety of tissues, including the brain, heart, and liver. It is composed of 21 distinct amino acid residues and has a calculated molecular mass of 33 kDa. The protein is highly conserved, with a sequence Similarity of 94% to human MB21, a protein that is known to play a role in the development and progression of cancer.

One of the key features of MB21D2 is its ability to interact with various transcription factors, including nuclear factor-kappa-B (NF-kappa-B), transcription factor-DNA binding protein (TF-DBP) and histone deacetylase (histone deacetylase). acetylase). These transcription factors play key roles in gene expression and regulation and are closely related to the occurrence and development of many diseases. Through interaction with these transcription factors, MB21D2 may have an impact on the treatment of various diseases.

Another important feature of MB21D2 is its expression in tumors. Studies have shown that MB21D2 is expressed in a variety of tumor tissues, including breast cancer, lung cancer, and prostate cancer. Furthermore, the expression level of MB21D2 was positively correlated with tumor growth and invasion capabilities. This suggests that MB21D2 may be a potential tumor therapeutic target.

In addition, MB21D2 also plays an important role in the cell cycle. MB21D2 is a deacetylase of histones, a major component of chromatin. Histone deacetylation is an important cell cycle regulatory mechanism through which it can regulate the structure and function of chromatin, thereby affecting gene expression and the cell cycle. The functional study of MB21D2 provides important ideas for understanding the cell cycle regulation mechanism and the mechanism of tumor development and development.

Biological functions of MB21D2

The biological functions of MB21D2 mainly involve tumor occurrence and development, cell cycle regulation, and cell-cell interactions.

First, MB21D2 plays an important role in tumorigenesis and progression. Studies have shown that the expression level of MB21D2 is positively correlated with tumor invasiveness, growth rate and survival. Moreover, the expression level of MB21D2 is also closely related to tumor metastasis and recurrence. These results suggest that MB21D2 may be a potential therapeutic target for tumors.

Secondly, MB21D2 also plays an important role in the cell cycle. MB21D2 is a deacetylase of histones, a major component of chromatin. Histone deacetylation is an important cell cycle regulatory mechanism through which it can regulate the structure and function of chromatin, thereby affecting gene expression and the cell cycle. Studies have shown that the expression level of MB21D2 is closely related to the S phase and G2 phase of the cell cycle, and its expression level is also closely related to the progression of the cell cycle and the progression of mitosis. These results indicate that MB21D2 plays an important role in cell cycle regulation and provide important ideas for in-depth study of cell cycle regulation mechanisms.

Finally, the biological functions of MB21D2 also involve cell-cell interactions. Studies have shown that MB21D2 is involved in intercellular signal transduction and cell adhesion. These results indicate that MB21D2 plays an important role in cell-cell interactions and provide important ideas for in-depth study of cell-cell interaction mechanisms.

Potential drugs and biomarkers

Potential drug and biomarker studies of MB21D2 have attracted widespread

Protein Name: Mab-21 Domain Containing 2

Functions: Probable nucleotidyltransferase that catalyzes the formation of cyclic dinucleotide second messenger in response to some unknown stimulus

The "MB21D2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MB21D2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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