MBD6: A Protein That Regulates Cell Growth, Differentiation and Apoptosis

Target Name: MBD6

NCBI ID: G114785

MBD6

MBD6: A Protein That Regulates Cell Growth, Differentiation and Apoptosis

MBD6, or Methyl-CpG binding domain protein 6, is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell growth, differentiation, and survival, and is involved in the development and progression of many diseases, including cancer.

One of the most significant functions of MBD6 is its ability to bind to specific DNA sequences, particularly the methylated CpG dinucleotide. This interaction between MBD6 and DNA is important for the regulation of gene expression and the development of cancer.

MBD6 is a member of the evolutionarily conserved superfamily of CpG-binding proteins, which includes other well-known proteins such as p53 and Rb. These proteins share a common structural feature, known as the CpG-binding domain, which is a region of the protein that contains a specific sequence of nucleotides that is able to bind to DNA in a specific way.

The MBD6 protein is composed of 191 amino acid residues and has a calculated molecular weight of 21 kDa. It is expressed in a variety of tissues, including muscle, lung, liver, and brain, and is involved in the regulation of cell growth, differentiation , and apoptosis.

One of the most significant functions of MBD6 is its ability to bind to specific DNA sequences, particularly the methylated CpG dinucleotide. This interaction between MBD6 and DNA is important for the regulation of gene expression and the development of cancer.

MBD6 has been shown to play a role in the regulation of cell growth and differentiation. It has been shown to inhibit the activity of the oncogene transforming growth factor beta (TGF-beta), which is a key regulator of cell growth and has been linked to the development of many diseases, including cancer.

MBD6 has also been shown to play a role in the regulation of cell apoptosis, or programmed cell death. It has been shown to promote the production of pro-apoptotic transcription factors, such as Bax, which is associated with the development of many diseases, including cancer.

MBD6 has also been shown to play a role in the regulation of inflammation. It has been shown to promote the production of pro-inflammatory cytokines, such as TNF-alpha, which is associated with the development of many inflammatory diseases.

MBD6 has been shown to play a role in the regulation of DNA replication, which is important for the development and progression of cancer. It has been shown to promote the production of DNA replication factors, which are important for the growth and development of cancer cells.

MBD6 has also been shown to play a role in the regulation of cell signaling pathways. It has been shown to interact with a variety of signaling proteins, including TGF-beta, Wnt, and Hedgehog, which are involved in the development and progression of many diseases, including cancer.

MBD6 has been shown to play a role in the regulation of cell adhesion. It has been shown to interact with a variety of adhesion molecules, including cadherins and integrins, which are involved in the development and progression of many diseases, including cancer.

MBD6 has also been shown to play a role in the regulation of cell migration. It has been shown to interact with a variety of signaling proteins, including TGF-beta and Ca2+, which are involved in the development and progression of many diseases, including cancer.

MBD6 has been shown to play a role in the regulation of cell differentiation. It has been shown to interact with a variety of signaling proteins, including TGF-beta and Wnt, which are involved in the development and progression of many diseases, including cancer.

MBD6 has also been shown to play a role in the regulation of cell survival. It has been shown to interact with a variety of signaling proteins, including

Protein Name: Methyl-CpG Binding Domain Protein 6

Functions: Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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