MBOAT4: A Potential Drug Target for Various Diseases (G619373)

Target Name: MBOAT4

NCBI ID: G619373

MBOAT4

MBOAT4: A Potential Drug Target for Various Diseases

MBOAT4 (Mucin-Binding Oligomerase Transmembrane Subunit 4) is a protein that is expressed in various cell types of the human body, including epithelial, endothelial, and mesenchymal tissues. It is a member of the Oligomerase superfamily and is a distant relative of the OCT family family. The protein encoded by the MBOAT4 gene is an intracellular protein that is expressed in a variety of tissues and organs. It functions as a regulator of gene expression in tissues and organs.

MBOAT4 plays an important role in many biological processes. During development, MBOAT4 is an important signal transduction molecule. Research shows that MBOAT4 plays a key role in neural tubeogenesis and development. During embryonic development, MBOAT4 interacts with the Wnt gene in the Wnt signaling pathway to promote the development of the neural tube.

MBOAT4 is also closely related to tumor occurrence and development. Studies have shown that the expression level of MBOAT4 is closely related to the prognosis and treatment response of various cancers. For example, the expression level of MBOAT4 correlates with the survival rate of lung cancer patients. In addition, MBOAT4 is also closely related to the progression and treatment response of cancers such as hepatocellular carcinoma and ovarian cancer.

MBOAT4 is also considered a potential target for many drugs. For example, MBOAT4 inhibitors have been shown to inhibit the growth and progression of a variety of tumors. In addition, MBOAT4 is closely related to the occurrence and development of many diseases and is therefore considered a potential drug target.

The structural and functional characteristics of MBOAT4 make it a potential drug target. Its expression level is closely related to the occurrence and development of various diseases, so it is considered an important drug target. Future research will continue to delve into the importance and function of MBOAT4 in organisms and explore the possibility of MBOAT4 as a drug target.

Protein Name: Membrane Bound O-acyltransferase Domain Containing 4

Functions: Catalyzes ghrelin acylation at 'Ser-3' using preferentially octanoyl-CoA, hexanoyl-CoA and decanoyl-CoA as acyl-CoA donors leading to ghrelin activity (PubMed:24045953, PubMed:18443287, PubMed:25562443, PubMed:28134508). In vitro uses also acyl-CoA donors of different lengths from short-chain (C2) to long-chain fatty acids (C16) knowing that acyl-CoA donors from butanoyl-CoA (C4) to dodecanoyl-CoA (C12) are more efficient compared to longer acyl-CoA donors, such as myristoyl-CoA (C14) and palmitoyl-CoA (C16) that are not efficient (PubMed:18443287)

The "MBOAT4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MBOAT4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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