Target Name: PHC2
NCBI ID: G1912
Review Report on PHC2 Target / Biomarker Content of Review Report on PHC2 Target / Biomarker
PHC2
Other Name(s): polyhomeotic homolog 2 | Polyhomeotic homolog 2, transcript variant 2 | hPH2 | polyhomeotic-like protein 2 | Early development regulatory protein 2 | PHC2_HUMAN | Polyhomeotic homolog 2, transcript variant 1 | Polyhomeotic-like protein 2 (isoform b) | Polyhomeotic-like protein 2 (isoform a) | Polyhomeotic-like 2 | polyhomeotic 2 | early development regulatory protein 2 | EDR2 | Polyhomeotic-like protein 2 | HPH2 | Early development regulator 2 (homolog of polyhomeotic 2) | Polyhomeotic 2 | PHC2 variant 1 | PH2 | PHC2 variant 2 | early development regulator 2 (homolog of polyhomeotic 2) | polyhomeotic-like 2

PHC2: A Potential Drug Target and Biomarker

PHC2 is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and pancreas. Its primary function is to regulate the production of platelets, which are essential for blood clotting.PHC2 has also been shown to play a role in the development and progression of certain diseases, such as cancer and neurodegenerative disorders.

As a potential drug target, PHC2 is being investigated for its ability to interfere with the activity of other proteins that contribute to the development of these diseases. By targeting PHC2 with small molecules or antibodies, researchers hope to prevent or reverse the negative effects of these proteins on cell proliferation and disease progression.

In addition to its potential as a drug target, PHC2 has also been identified as a potential biomarker for certain diseases. Its expression has been shown to be elevated in the brains of individuals with certain neurological disorders, such as Alzheimer's disease and Parkinson's disease. This suggests that PHC2 may be a useful diagnostic or therapeutic target for these conditions.

The identification of PHC2 as a potential drug target and biomarker highlights the growing interest in this protein and its potential impact on human health. Further research is needed to fully understand its functions and potential applications in medicine.

Since its discovery, PHC2 has been shown to have a number of potential applications in drug development. For example, studies have shown that inhibiting the activity of PHC2 can lead to the growth of cancer cells in a cell culture setting. Additionally, PHC2 has been shown to reduce the formation of blood clots in mice, which may have implications for the treatment of cardiovascular disease.

While more research is needed to fully understand the functions of PHC2 and its potential as a drug target and biomarker, its identification has sparked significant interest in this protein among researchers and the pharmaceutical industry. As the field of pharmacology continues to evolve, PHC2 is likely to play an important role in the development of new treatments for a variety of diseases.

Protein Name: Polyhomeotic Homolog 2

Functions: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility

The "PHC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PHC2-AS1 | PHC3 | Phenylalanyl-tRNA synthetase | PHETA1 | PHETA2 | PHEX | PHEX-AS1 | PHF1 | PHF10 | PHF11 | PHF12 | PHF13 | PHF14 | PHF19 | PHF2 | PHF2-ARID5B complex | PHF20 | PHF20L1 | PHF21A | PHF21B | PHF23 | PHF24 | PHF2P1 | PHF2P2 | PHF3 | PHF5A | PHF6 | PHF7 | PHF8 | PHGDH | PHGR1 | PHIP | PHKA1 | PHKA1-AS1 | PHKA2 | PHKA2-AS1 | PHKB | PHKG1 | PHKG2 | PHLDA1 | PHLDA2 | PHLDA3 | PHLDB1 | PHLDB2 | PHLDB3 | PHLPP1 | PHLPP2 | Phosphatidylinositol 3-kinase (PI3K) | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16 | PI3 | PI4K2A | PI4K2B | PI4KA | PI4KAP1 | PI4KAP2 | PI4KB | PIANP | PIAS1 | PIAS2 | PIAS3 | PIAS4 | PIBF1 | PICALM | PICART1 | PICK1