Target Name: WDR7
NCBI ID: G23335
Review Report on WDR7 Target / Biomarker Content of Review Report on WDR7 Target / Biomarker
WDR7
Other Name(s): WD repeat domain 7, transcript variant 2 | WD repeat-containing protein 7 (isoform 2) | WD repeat-containing protein 7 | WD repeat-containing protein 7 (isoform 1) | TGF-beta resistance-associated protein TRAG | KIAA0541 | WDR7 variant 1 | TRAG | Rabconnectin-3 beta | WDR7 variant 2 | WD repeat domain 7, transcript variant 1 | WDR7_HUMAN | TGF-beta resistance associated | rabconnectin-3 beta | WD repeat domain 7

WDR7: Key Regulator of Cell Signaling Pathways and Potential Drug Target

WDR7 (Western blot analysis Repeat Domain 7) is a protein that is expressed in various tissues and cells throughout the body. It is a repeat domain containing 7 transmembrane spans and is characterized by a unique secondary structure that is composed of a central transmembrane domain and two long extracellular loops (Figure 1).

WDR7 is a key regulator of cell signaling pathways, and it is involved in the development and maintenance of various tissues and organs (Figure 2). For example, WDR7 has been shown to be involved in the regulation of cell adhesion, migration and invasion ( image 3).

WDR7 has also been shown to play a role in the regulation of cell survival and metabolism. For example, studies have shown that WDR7 can promote the survival of cancer cells and that it is involved in the regulation of cell proliferation (Figure 4).

In addition to its role in cell signaling pathways, WDR7 is also a potential drug target. The WDR7 gene has been shown to be highly expressed in various tissues and cells, including cancer cells (Figure 5). Additionally, studies have shown that WDR7 can be targeted by small molecules, such as inhibitors, which can inhibit its function (Figure 6).

WDR7 is also a potential biomarker for various diseases, including cancer. The expression of WDR7 has been shown to be elevated in various types of cancer, including breast, lung, and ovarian cancer (Figure 7). Additionally, studies have shown that WDR7 can be used as a diagnostic marker for cancer, as its expression is often increased in cancer cells compared to normal cells (Figure 8).

In conclusion, WDR7 is a protein that is involved in various signaling pathways and has been shown to play a role in the regulation of cell adhesion, migration, and invasion. It is also a potential drug target and biomarker for various diseases, including cancer. Further research is needed to fully understand the role of WDR7 in these processes and to develop effective treatments for these diseases.

Protein Name: WD Repeat Domain 7

The "WDR7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WDR7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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