Target Name: CACNG5
NCBI ID: G27091
Review Report on CACNG5 Target / Biomarker Content of Review Report on CACNG5 Target / Biomarker
CACNG5
Other Name(s): CCG5_HUMAN | calcium voltage-gated channel auxiliary subunit gamma 5 | Neuronal voltage-gated calcium channel gamma-5 subunit | Voltage-dependent calcium channel gamma-5 subunit | MGC126656 | MGC126682 | calcium channel, voltage-dependent, gamma subunit 5 | neuronal voltage-gated calcium channel gamma-5 subunit | transmembrane AMPAR regulatory protein gamma-5 | TARP gamma-5 | Transmembrane AMPAR regulatory protein gamma-5 | Voltage-dependent calcium channel gamma-5 subunit (isoform 1) | CACNG5 variant 1 | Calcium voltage-gated channel auxiliary subunit gamma 5, transcript variant 1

CACNG5: A Promising Drug Target and Biomarker

CACNG5 (CCG5-HUMAN) is a gene that encodes a protein known as CACNG5, which is a member of the CCR4-like family. This protein is expressed in various tissues and organs throughout the body, including the brain, heart, liver, and stem cells. CACNG5 has been shown to play a role in several cellular processes, including cell signaling, migration, and invasion.

One of the most promising aspects of CACNG5 is its potential as a drug target. CACNG5 has been shown to interact with several different signaling pathways, including the TGF-β pathway and the PI3K/Akt pathway. These signaling pathways are involved in a wide range of cellular processes, including cell growth, differentiation, and survival.

In addition to its potential as a drug target, CACNG5 has also been shown to be a potential biomarker for several diseases, including cancer. For example, studies have shown that high levels of CACNG5 expression are associated with poor prognosis in patients with pancreatic cancer. Additionally, CACNG5 has been shown to be expressed in a variety of cancer types, including breast, ovarian, and colorectal cancer.

Another promising aspect of CACNG5 is its ability to modulate the activity of other proteins. This is known as \"drug-like\" activity, and it refers to the ability of small molecules or other substances to mimic the effects of drugs on a target protein without actually interacting with it. CACNG5 has been shown to have drug-like activity, and this may be a promising strategy for the development of new treatments.

Overall, CACNG5 is a gene that has significant potential as a drug target and biomarker. Further research is needed to fully understand its role in cellular processes and its potential as a therapeutic agent.

Protein Name: Calcium Voltage-gated Channel Auxiliary Subunit Gamma 5

Functions: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity)

The "CACNG5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CACNG5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CACNG6 | CACNG7 | CACNG8 | CACTIN | CACTIN-AS1 | CACUL1 | CACYBP | CAD | CADM1 | CADM2 | CADM3 | CADM3-AS1 | CADM4 | CADPS | CADPS2 | CAGE1 | CAHM | CALB1 | CALB2 | CALCA | CALCB | Calcium channel | Calcium release-activated channel (CRAC) | Calcium-activated chloride channel regulators | Calcium-Activated K(Ca) Potassium Channel | CALCOCO1 | CALCOCO2 | CALCR | CALCRL | CALCRL-AS1 | CALD1 | CALHM1 | CALHM2 | CALHM3 | CALHM4 | CALHM5 | CALHM6 | CALM1 | CALM2 | CALM2P1 | CALM2P2 | CALM3 | CALML3 | CALML3-AS1 | CALML4 | CALML5 | CALML6 | Calmodulin | CALN1 | Calpain | Calpain-13 | Calprotectin | CALR | CALR3 | CALU | CALY | CAMK1 | CAMK1D | CAMK1G | CAMK2A | CAMK2B | CAMK2D | CAMK2G | CAMK2N1 | CAMK2N2 | CAMK4 | CAMKK1 | CAMKK2 | CAMKMT | CAMKV | CAMLG | CAMP | cAMP Phosphodiesterase | cAMP Responsive Element Binding Protein (CREB) | cAMP-Dependent protein kinase (PKA) | CAMSAP1 | CAMSAP2 | CAMSAP3 | CAMTA1 | CAMTA2 | CAND1 | CAND1.11 | CAND2 | Cannabinoid receptor | CANT1 | CANX | Cap-binding complex | CAP1 | CAP2 | CAPG | CAPN1 | CAPN10 | CAPN10-DT | CAPN11 | CAPN12 | CAPN13 | CAPN14 | CAPN15 | CAPN2 | CAPN3