Target Name: DENR
NCBI ID: G8562
Review Report on DENR Target / Biomarker Content of Review Report on DENR Target / Biomarker
DENR
Other Name(s): density regulated re-initiation and release factor | DRP | SMAP-3 | Smooth muscle cell associated protein-3 | smooth muscle cell associated protein-3 | Density-regulated protein | DENR_HUMAN | Smooth muscle cell-associated protein 3 | Density regulated re-initiation and release factor | Protein DRP1 | DRP1

DENR: A Protein That Regulates Cell Division and Cell Growth

DENR (Density-Regulated Re-Initiation and Release Factor) is a protein that plays a crucial role in cell biology, particularly in the regulation of cell division and the control of cell growth. It is a key factor in the process of cell division, where the cell grows and divides, and it helps to ensure that the cell division process is controlled and orderly.

Research has shown that DENR is involved in many different cellular processes, including the regulation of cell growth, the control of cell division, and the regulation of cell death. It is also involved in the regulation of the cytoskeleton, which is the structure that gives cells shape and stability, as well as in the regulation of the cell membrane.

DENR is a protein that is expressed in many different cell types, including neurons, muscle cells, and epithelial cells. It is often used as a drug target or biomarker, particularly in the development of cancer.

One of the key functions of DENR is its role in cell division. DENR helps to ensure that the cell division process is controlled and orderly by regulating the production of new DNA and the separation of the chromosomes at the end of cell division. This helps to ensure that each new cell that is produced has an accurate copy of the genetic information that was passed down from the parent cell.

In addition to its role in cell division, DENR is also involved in the regulation of cell growth and the control of cell death. It helps to ensure that cells are not allowed to grow too large, which can lead to the formation of tumors. It also helps to ensure that cells are able to die when they are no longer needed, which is an important part of the regulation of cell death.

DENR is also involved in the regulation of the cytoskeleton, which is the structure that gives cells shape and stability. It helps to ensure that the cytoskeleton is properly organized and that the cell is able to move and function properly.

In addition to its role in cell biology, DENR is also involved in the regulation of many different cellular processes, including the regulation of the immune system, the regulation of the blood clotting system, and the regulation of the blood pressure.

As a result of its involvement in so many different cellular processes, DENR is a potential drug target or biomarker for a wide range of diseases. For example, research has shown that DENR may be a potential drug target for cancer, particularly if it is involved in the regulation of cell division and the control of cell death.

In addition to its potential as a drug target or biomarker, DENR is also of interest as a potential therapeutic agent for a wide range of other diseases. For example, it may be useful in the treatment of cancer by inhibiting the activity of DENR, which could help to ensure that cells are able to divide and grow properly. It may also be useful in the treatment of other diseases, such as heart disease, by regulating the activity of DENR and ensuring that cells are able to die when they are no longer needed.

Overall, DENR is a protein that plays a crucial role in cell biology, particularly in the regulation of cell division and the control of cell growth. It is a potential drug target or biomarker for a wide range of diseases and may be an important target for researchers in the future.

Protein Name: Density Regulated Re-initiation And Release Factor

Functions: May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1

The "DENR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DENR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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