CFAP58: A Potential Drug Target and Biomarker (G159686)

Target Name: CFAP58

NCBI ID: G159686

CFAP58

CFAP58: A Potential Drug Target and Biomarker

CFAP58, also known as OTTHUMP00000020442, is a protein that is expressed in various tissues throughout the body, including the skin, hair, and nails. It is a member of the cytoskeleton and is involved in the formation and maintenance of the cell structure.

CFAP58 has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. The protein is known to interact with several other proteins, including FBN1, FBN2, and FBN3, which are all involved in the formation of blood vessels. This suggests that CFAP58 may be a useful target for treating conditions related to blood vessel formation, such as heart disease and cancer.

In addition to its potential as a drug target, CFAP58 has also been shown to be a potential biomarker for several diseases. For example, studies have shown that high levels of CFAP58 are associated with the development of certain types of cancer, including skin cancer and breast cancer. Additionally, high levels of CFAP58 have been detected in the skin, which suggests that it may be a useful indicator of skin health and the risk of certain skin diseases.

CFAP58 is also involved in several cellular processes that are important for normal tissue growth and development. For example, it plays a role in the formation of new cells in the skin, hair, and nails, and it helps to maintain the structure of these tissues. This suggests that changes in the levels or activity of CFAP58 may be a sign of underlying cellular or molecular changes, such as aging or certain types of cancer.

The unique structure of CFAP58 also makes it an attractive target for drug development. The protein is known to have a unique farnesylated cysteine residue, which is a hallmark of protein stability and may make it more resistant to certain types of drugs. Additionally, the protein is involved in several cellular processes that are critical for normal function, which may make it more difficult to target and may reduce the risk of unintended side effects.

CFAP58 is also a good candidate as a drug target because it is expressed in multiple tissues and cells throughout the body, which makes it more accessible to drugs. This is important because it allows researchers to test the effects of drugs on multiple cellular processes and to identify potential side effects that may be relevant to a larger number of patients.

In conclusion, CFAP58 is a protein that has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. It is also a potential biomarker for several diseases and has been shown to be involved in the formation of new cells in the skin, hair, and nails. The unique structure of CFAP58 makes it an attractive target for drug development, and further studies are needed to determine its potential as a therapeutic agent.

Protein Name: Cilia And Flagella Associated Protein 58

Functions: Has an essential role in the assembly and organization of the sperm flagellar axoneme (PubMed:32791035). Required for the elongation of the primary cilium and sperm flagellar midpiece via modulation of the Notch signaling pathway (By similarity)

The "CFAP58 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CFAP58 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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