Target Name: WDR53
NCBI ID: G348793
Review Report on WDR53 Target / Biomarker Content of Review Report on WDR53 Target / Biomarker
WDR53
Other Name(s): WDR53 variant 1 | WD repeat domain 53 | WD repeat domain 53, transcript variant 1 | WD domain, G-beta repeat-containing protein | WD repeat-containing protein 53 (isoform a) | WDR53_HUMAN | WD repeat-containing protein 53

WDR53: A Non-Coding RNA Molecule as A Potential Drug Target and Biomarker

WDR53 (WDR53 variant 1) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments.

WDR53 is a transcribed RNA molecule that is found in various tissues and cells throughout the body. It is a key player in the Wnt signaling pathway, a pathway that regulates cell growth, differentiation, and development. The Wnt signaling pathway has been implicated in the development and progression of many diseases, including cancer.

One of the unique features of WDR53 is its ability to interact with other molecules and structures in the Wnt signaling pathway. This interaction has been shown to play a role in the regulation of cell proliferation and survival. WDR53 has been shown to interact with the protein (SPI) and receptor tyrosine kinase (RTK), these molecules play important roles in cell growth and apoptosis.

Expression levels of WDR53 are also affected by many diseases, including cancer. Studies have shown that WDR53 expression levels are closely related to the progression and treatment response of many cancers. For example, WDR53 expression levels are positively correlated with progression and treatment response in cancers such as breast, lung, and hepatocellular carcinoma.

In addition, WDR53 is also considered as a potential biomarker. By detecting the expression level of WDR53, patients' disease progression and treatment effects can be detected and evaluated early. In cancer treatment, monitoring WDR53 levels can help doctors determine whether patients are responding to treatment, as well as assess the long-term effects of treatment.

The structure and function of WDR53 also make it a potential drug target. Researchers are exploring the use of WDR53 as a target to treat cancer and other diseases. For example, using genetic engineering technology, WDR53 can be converted into a switchable RNA molecule, thereby inhibiting its binding to SPI and RTK, thereby hindering its growth and expansion of cells. In addition, the expression level of WDR53 can also be used as a biomarker to evaluate the therapeutic effect.

Overall, WDR53 (WDR53 variant 1) is a potential drug target and biomarker that can affect cell growth and apoptosis and is related to many diseases. Researchers are actively exploring the applications of WDR53 to develop new treatments and evaluate treatment efficacy. With the continuous advancement of technology, we are expected to see more applications of WDR53 in the future, bringing more help to human health.

Protein Name: WD Repeat Domain 53

The "WDR53 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WDR53 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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