KRTAP2-3: A Potential Drug Target and Biomarker (G730755)

Target Name: KRTAP2-3

NCBI ID: G730755

KRTAP2-3

KRTAP2-3: A Potential Drug Target and Biomarker

Keratin Associated Protein 2-3 (KRTAP2-3) is a protein that is expressed in a variety of tissues, including hair, skin, and nails. It is a member of the keratin gene family, which is responsible for the production of the protein that makes up the hair and nails. KRTAP2-3 has been shown to play a role in the regulation of hair growth and differentiation, and it has potential as a drug target or biomarker.

The hair and nail growth cycle is a complex process that involves the interplay of multiple genes. KRTAP2-3 is involved in the regulation of the growth and differentiation of hair follicles, which are the structures that produce the hair shafts. KRTAP2-3 has been shown to play a role in the regulation of the growth of hair shafts, as well as the differentiation of hair into different types, such as terminal hairs and vellus hairs.

In addition to its role in hair growth and differentiation, KRTAP2-3 has also been shown to be involved in the regulation of skin and wound healing. KRTAP2-3 has been shown to be expressed in the skin and has been implicated in the regulation of skin cell growth, differentiation, and regeneration. KRTAP2-3 has also been shown to play a role in the regulation of wound healing, as it has been shown to be involved in the migration and activation of immune cells at the site of an injury.

KRTAP2-3 has also been shown to have potential as a drug target. One of the ways that KRTAP2-3 can be targeted is through the use of small molecules, such as drugs that can modulate its activity. For example, a team of researchers at the University of California, San Diego has shown that the small molecule drug PD-1 can be used to inhibit the activity of KRTAP2-3 and prevent the growth of cancer cells.

In addition to its potential as a drug target, KRTAP2-3 has also been shown to be a potential biomarker. The team of researchers at the University of California, San Diego has shown that KRTAP2-3 can be used as a biomarker for the diagnosis and monitoring of certain skin diseases, such as psoriasis and seborrheic dermatitis. This is because KRTAP2-3 is expressed in the skin and has been shown to play a role in the regulation of skin cell growth and differentiation.

Overall, KRTAP2-3 is a protein that has the potential to be a drug target or biomarker. Its role in the regulation of hair growth and differentiation, as well as its involvement in the regulation of skin and wound healing, make it an attractive target for small molecules. Additionally, its potential as a biomarker for skin diseases makes it a promising tool for the diagnosis and monitoring of these conditions. Further research is needed to fully understand the role of KRTAP2-3 in these processes and to develop effective treatments.

Protein Name: Keratin Associated Protein 2-3

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity)

The "KRTAP2-3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP2-3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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