KRTAP19-8: A Potential Drug Target and Biomarker (G728299)

Target Name: KRTAP19-8

NCBI ID: G728299

KRTAP19-8

KRTAP19-8: A Potential Drug Target and Biomarker

Keratin-associated protein 19-8 (KRTAP19-8) is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to study, and its potential as a drug may have significant implications for the treatment of these diseases.

The protein KRTAP19-8 is a type of transmembrane protein that is expressed in various tissues and organs, including skin, hair, nails, and the nervous system. It is composed of 19 distinct amino acid residues and has a calculated molecular weight of 21.4 kDa. KRTAP19-8 is highly conserved throughout various species, which suggests that it has a critical role in the function of these proteins.

One of the key features of KRTAP19-8 is its ability to interact with various proteins, including tyrosine hydroxylase (TH) and heat shock protein (HSP) proteins. TH and HSP proteins are involved in the regulation of cellular processes that are critical for cell growth, differentiation, and survival. By interacting with these proteins, KRTAP19-8 is able to modulate their activity and function.

In addition to its potential role in cell signaling, KRTAP19-8 has also been shown to play a role in the regulation of cellular waste removal. It is involved in the transport of various types of cellular waste, including dead cells and damaged proteins, to the endoplasmic reticulum for degradation. This function is critical for maintaining cellular homeostasis and may be relevant to the treatment of various diseases, including cancer.

KRTAP19-8 has also been shown to be involved in the regulation of cellular adhesion. It is a component of the cadherin protein complex, which is involved in cell-cell adhesion and has been implicated in various diseases, including cancer. By modulating the activity of cadherins, KRTAP19-8 may be involved in the development and progression of these diseases.

In terms of its potential as a drug target, KRTAP19-8 is an attractive target due to its unique structure and the role it plays in various cellular processes. Its ability to interact with TH and HSP proteins makes it a potential target for small molecules that can modulate these proteins' activity. Additionally, its role in cell signaling and waste removal may make it a potential target for drugs that are aimed at modulating cellular homeostasis.

In conclusion, KRTAP19-8 is a protein that has the potential to be a drug target and biomarker for various diseases. Its unique structure and function make it an attractive target for small molecules that can modulate its activity. Further research is needed to fully understand the role of KRTAP19-8 in cellular processes and its potential as a drug.

Protein Name: Keratin Associated Protein 19-8

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP19-8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP19-8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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