Target Name: KRTAP21-1
NCBI ID: G337977
Review Report on KRTAP21-1 Target / Biomarker Content of Review Report on KRTAP21-1 Target / Biomarker
KRTAP21-1
Other Name(s): KR211_HUMAN | keratin-associated protein 21-1 | KAP21.1 | keratin associated protein 21-1 | Keratin associated protein 21-1 | Keratin-associated protein 21-1

KRTAP21-1: A Potential Drug Target and Biomarker

KRTAP21-1 (KR211_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and kidneys. It is a member of the KRTAP family, which includes several related proteins that play important roles in intracellular signaling.

One of the unique features of KRTAP21-1 is its ability to interact with several different signaling pathways, including the PI3K/Akt signaling pathway, the TGF-β signaling pathway, and the NF-kappa-B signaling pathway. This makes KRTAP21-1 a promising drug target for a variety of diseases.

In addition to its potential as a drug target, KRTAP21-1 is also a potential biomarker for several diseases. For example, altered levels of KRTAP21-1 have been observed in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Additionally, KRTAP21-1 has been shown to be involved in several key signaling pathways that are involved in the development and progression of these diseases, further supporting its potential as a biomarker.

KRTAP21-1 has also been shown to play important roles in several physiological processes in the body. For example, it is involved in the regulation of cell adhesion, cell migration, and the formation of blood vessels. It is also involved in the regulation of inflammation and immune responses.

In conclusion, KRTAP21-1 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Its unique ability to interact with multiple signaling pathways and its involvement in several important physiological processes make it an attractive target for research and development of new treatments. Further research is needed to fully understand the role of KRTAP21-1 in disease and to develop effective treatments.

Protein Name: Keratin Associated Protein 21-1

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP21-1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP21-1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KRTAP21-2 | KRTAP21-3 | KRTAP22-1 | KRTAP22-2 | KRTAP23-1 | KRTAP25-1 | KRTAP26-1 | KRTAP27-1 | KRTAP29-1 | KRTAP3-1 | KRTAP3-2 | KRTAP3-3 | KRTAP4-1 | KRTAP4-11 | KRTAP4-12 | KRTAP4-2 | KRTAP4-3 | KRTAP4-4 | KRTAP4-5 | KRTAP4-6 | KRTAP4-7 | KRTAP4-8 | KRTAP4-9 | KRTAP5-1 | KRTAP5-10 | KRTAP5-11 | KRTAP5-14P | KRTAP5-2 | KRTAP5-3 | KRTAP5-4 | KRTAP5-5 | KRTAP5-7 | KRTAP5-8 | KRTAP5-9 | KRTAP5-AS1 | KRTAP6-1 | KRTAP6-2 | KRTAP6-3 | KRTAP7-1 | KRTAP8-1 | KRTAP9-1 | KRTAP9-2 | KRTAP9-3 | KRTAP9-4 | KRTAP9-6 | KRTAP9-7 | KRTAP9-8 | KRTAP9-9 | KRTCAP2 | KRTCAP3 | KRTDAP | KSR1 | KSR1P1 | KSR2 | KTI12 | KTN1 | KTN1-AS1 | KXD1 | KY | KYAT1 | KYAT3 | KYNU | L-Type calcium channel | L-type voltage-dependent calcium channel complex | L1CAM | L1CAM-AS1 | L1TD1 | L2HGDH | L3HYPDH | L3MBTL1 | L3MBTL2 | L3MBTL3 | L3MBTL4 | L3MBTL4-AS1 | LACAT1 | LACC1 | LACRT | Lactate Dehydrogenase (LDH) | LACTB | LACTB2 | LACTB2-AS1 | LACTBL1 | LAD1 | LAG3 | LAGE3 | LAIR1 | LAIR2 | LALBA | LAMA1 | LAMA2 | LAMA3 | LAMA4 | LAMA5 | LAMB1 | LAMB2 | LAMB2P1 | LAMB3 | LAMB4 | LAMC1 | LAMC1-AS1