KRTAP2-2: A Potential Drug Target and Biomarker (G728279)

Target Name: KRTAP2-2

NCBI ID: G728279

KRTAP2-2

KRTAP2-2: A Potential Drug Target and Biomarker

Keratin associated protein 2-2 (KRTAP2-2) is a protein that is expressed in a variety of tissues, including hair, skin, and nails. It is a member of the keratin family of proteins, which are responsible for the structure and function of hair and nails. KRTAP2-2 has been identified as a potential drug target and biomarker due to its unique structure and function.

The KRTAP2-2 protein is composed of 214 amino acid residues and has a calculated molecular mass of 24.2 kDa. It has a single transmembrane region and a cytoplasmic tail. KRTAP2-2 is associated with the cytoplasm and is located at the end of the cytoplasmic tail. It has been shown to interact with various proteins, including the transcription factor, nuclear factor of actin (NF- actin), and the protein kinase, serine/thymidine kinase (S/TK).

KRTAP2-2 has been shown to play a role in various biological processes, including cell growth, differentiation, and inflammation. It has been shown to be involved in the regulation of cell cycle progression, cell adhesion, and the production of connective tissue. KRTAP2-2 has also been shown to play a role in the regulation of the immune response and inflammation.

As a potential drug target, KRTAP2-2 has been shown to have a high potential for drug development due to its unique structure and function. It is a protein that is expressed in a variety of tissues and has been shown to play a role in various biological processes. This makes it an attractive target for drug development due to its high potential for efficacy and its ease of targeting.

In addition to its potential as a drug target, KRTAP2-2 has also been shown to be a potential biomarker. Its unique structure and function make it an attractive candidate for use as a biomarker for various diseases, including cancer, autoimmune diseases, and neurodegenerative diseases.

KRTAP2-2 has been shown to be involved in the regulation of cell cycle progression and has been shown to interact with the transcription factor, nuclear factor of actin (NF-actin). This suggests that it may be involved in the regulation of cell growth and differentiation. Additionally, KRTAP2-2 has been shown to play a role in the regulation of the immune response and inflammation, which may make it an attractive target for the development of vaccines and therapies for autoimmune diseases.

In conclusion, KRTAP2-2 is a protein that has a unique structure and function and has been shown to play a role in various biological processes. As a potential drug target and biomarker, KRTAP2-2 has a high potential for drug development and research. Further research is needed to fully understand its role in various biological processes and its potential as a drug target and biomarker.

Protein Name: Keratin Associated Protein 2-2

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity)

The "KRTAP2-2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP2-2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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