Target Name: GPR152
NCBI ID: G390212
Review Report on GPR152 Target / Biomarker Content of Review Report on GPR152 Target / Biomarker
GPR152
Other Name(s): GP152_HUMAN | G protein-coupled receptor 152 (GPR152) | G-protein coupled receptor PGR5 | G protein-coupled receptor 152 | G protein-coupled receptor PGR5 | PGR5 | Probable G-protein coupled receptor 152

GPR152: A Potential Drug Target and Biomarker

GPR152 (GP152_HUMAN), a protein encoded by the human gene GP152, is a potential drug target and biomarker associated with various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. GPR152 has been shown to play a crucial role in the development and progression of these diseases, and its dysfunction has been associated with the loss of numerous cellular processes that maintain tissue homeostasis and physiological functions.

The GPR152 protein is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a central role in cellular signaling. Members of the GPCR family usually have seven different isoforms, These isomers exert different biological effects within cells. GPR152 is a gene encoding a protein encoded by the human genome.

Variations in the GPR152 gene are associated with a variety of diseases. For example, variations in the GPR152 gene are associated with cancer progression and response to treatment. Some studies have shown that variations in the GPR152 gene are associated with poor prognosis in various cancers, including lung cancer, liver cancer, breast cancer, etc. In addition, mutations in the GPR152 gene are also related to neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease.

The expression level of GPR152 gene is also involved in the progression of various diseases. For example, expression levels of the GPR152 gene are positively correlated with the progression of neurodegenerative diseases and cancer. Some studies have also shown that the expression level of the GPR152 gene is related to the progression of cardiovascular disease and treatment response.

The function of GPR152 gene is also related to various diseases. For example, the protein encoded by the GPR152 gene can regulate intracellular calcium ion concentration and thereby participate in cell signaling. In addition, the protein encoded by the GPR152 gene can also regulate intracellular lipid synthesis and participate in intracellular energy metabolism. The function of GPR152 gene is also related to cellular immune response and can regulate the activity of T cells and B cells.

Protein Name: G Protein-coupled Receptor 152

Functions: Orphan receptor

The "GPR152 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPR152 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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