MAPK13: A Protein That Regulates Cell Signaling and Cellular Processes

Target Name: MAPK13

NCBI ID: G5603

MAPK13

MAPK13: A Protein That Regulates Cell Signaling and Cellular Processes

MAPK13, also known as mitogen-activated protein kinase 13, is a protein that plays a crucial role in cell signaling. It is a member of the MAPK family, which includes several related proteins that regulate cellular responses to various stimuli, including growth factors and cytokines.

MAPK13 is involved in a wide range of cellular processes, including cell growth, differentiation, and survival. It is a key regulator of the cytoskeleton, which is the structure that gives cells their shape and helps them maintain their stability. It also plays a role in cell adhesion, migration, and the formation of tissues such as muscle and skin.

MAPK13 is a protein that is expressed in many different types of cells in the body, including muscle, nerve, and epithelial cells. It is often used as a drug target or biomarker because of its involvement in a wide range of cellular processes.

One of the main functions of MAPK13 is to regulate cell growth and cell differentiation. It is involved in the production of the cytoskeleton, which is the structure that gives cells their shape and helps them maintain their stability. It also plays a role in the regulation of cell proliferation and the control of cell differentiation.

MAPK13 is also involved in the regulation of cell adhesion and migration. It is a key regulator of cell-cell adhesion, which is the process by which cells stick together to form tissues. It also plays a role in the regulation of cell migration, which is the movement of cells from one location to another in the body.

MAPK13 is also involved in the regulation of cell survival. It is a key regulator of cell survival, helping cells to adapt to various environmental conditions and avoiding damage that could otherwise cause cells to die.

MAPK13 is a protein that is expressed in many different types of cells in the body. It is often used as a drug target or biomarker because of its involvement in a wide range of cellular processes. As a drug target, MAPK13 can be targeted with small molecules or antibodies to inhibit its activity and reduce the production of cellular signaling proteins. This can lead to a variety of potential therapeutic benefits, including the treatment of various diseases and conditions. As a biomarker, MAPK13 can be used to monitor the effectiveness of different treatments and to predict the outcomes of clinical trials.

In conclusion, MAPK13 is a protein that plays a crucial role in cell signaling and is involved in a wide range of cellular processes. It is often used as a drug target or biomarker due to its involvement in various cellular processes and its potential therapeutic benefits. Further research is needed to fully understand the role of MAPK13 in cell signaling and its potential as a drug target or biomarker.

Protein Name: Mitogen-activated Protein Kinase 13

Functions: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K. Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1. Mediates UV irradiation induced up-regulation of the gene expression of CXCL14. Plays an important role in the regulation of epidermal keratinocyte differentiation, apoptosis and skin tumor development. Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway. MAPK13 also phosphorylates and down-regulates PRKD1 during regulation of insulin secretion in pancreatic beta cells

The "MAPK13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAPK13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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