MAP6D1: A Protein Target for Drug Development (G79929)

Target Name: MAP6D1

NCBI ID: G79929

MAP6D1

MAP6D1: A Protein Target for Drug Development

MAP6D1, also known as STOP-like protein 21 (SLP-21), is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is characterized by its unique structure, which consists of a long N-terminus, a catalytic domain, and a short C-terminus.

MAP6D1 functions as a negative regulator of microtubules, which are dynamic structures that play a critical role in the proper functioning of various cellular processes. Microtubules are made up of a protein called tau, which is modified with a variety of post-translational modifications to give it its unique structure and stability.

MAP6D1 is well-known for its role in the regulation of microtubule dynamics and stability. It has been shown to interact with a variety of microtubule-associated proteins, including microtubule-associated protein 2 (MAP2), microtubule-associated protein 3 (MAP3), and microtubule-associated protein 4 (MAP4).

MAP6D1 has also been shown to play a role in the regulation of cellular processes that are critical for cell survival, such as cell division, angiogenesis, and neurodegeneration. For example, studies have shown that MAP6D1 is involved in the regulation of cell division in various tissues, including the brain, and that it plays a role in the development of neurodegenerate diseases.

In addition to its role in cell biology, MAP6D1 has also been shown to be a potential drug target. Several studies have shown that MAP6D1 can be targeted by small molecules, including inhibitors of the protein's activity. These small molecules have been shown to have a variety of different effects on MAP6D1, including the ability to inhibit its catalytic activity and the ability to stabilize microtubules.

The potential utility of MAP6D1 as a drug target is due to its unique structure and the various functions that it has been shown to play in cell biology. As more research is conducted on MAP6D1, it is likely that new compounds will be identified that can further our understanding of its role in cell biology and its potential as a drug target.

In conclusion, MAP6D1 is a protein that has critical roles in the regulation of microtubule dynamics and stability, as well as in the development of various cellular processes that are critical for cell survival. Its unique structure and various functions make it an attractive target for drug development, and further research is likely to uncover its full potential as a drug and diagnostic agent.

Protein Name: MAP6 Domain Containing 1

Functions: May have microtubule-stabilizing activity

The "MAP6D1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAP6D1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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