MAP7D2: A Potential Drug Target and Biomarker (G256714)

Target Name: MAP7D2

NCBI ID: G256714

MAP7D2

MAP7D2: A Potential Drug Target and Biomarker

MAP7D2, also known as MAP7D2 protein or MAP7D2 gene, is a protein that localizes to the endoplasmic reticulum (ER) and is involved in the regulation of mitochondrial dynamics. It is a member of the transmembrane protein family 7, which includes several other well- known proteins such as the heat shock protein (HSP70) and the Na+/K+-ATPase (NATPase).MAP7D2 has been shown to play a crucial role in regulating the levels of intracellular reactive oxygen species (ROS), which can cause damage to cellular components and contribute to various diseases, including neurodegenerative disorders, cancer, and aging.

The MAP7D2 gene has four splice variants, isoform 1, isoform 2, isoform 3, and isoform 4, which result in differences in the level of expression and localization of the protein. The most abundant isoform, MAP7D2-ISO1, is the one that is Mainly expressed in the brain and other organ tissues, while the less abundant isoform, MAP7D2-ISO3, is mainly expressed in the liver.

MAP7D2 functions as a protein that can interact with various cellular components, including transcription factors, DNA-protein binding proteins, and metabolic enzymes. It is involved in the regulation of mitochondrial dynamics and in the detoxification of ROS. It also plays a role in the Regulation of cellular signaling pathways, including the production of reactive oxygen species, which can cause damage to cellular components and contribute to various diseases.

MAP7D2 has been shown to play a crucial role in the regulation of cellular homeostasis. It helps to maintain the stability of cellular cytosol and inner membrane potential, which is critical for the proper functioning of the cell. It also helps to maintain the stability of mitochondrial dynamics, which is essential for the proper functioning of the cell energy metabolism.

MAP7D2 has also been shown to be involved in the regulation of cellular signaling pathways. It is involved in the production of reactive oxygen species, which can cause damage to cellular components and contribute to various diseases. of autophagy, which is a critical mechanism for the elimination of damaged or unnecessary cellular components.

MAP7D2 has been shown to play a crucial role in the regulation of neurodegenerative disorders. It is involved in the production of reactive oxygen species, which can cause damage to neural cells and contribute to the development of neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. It is also involved in the regulation of cellular signaling pathways, which can contribute to the progression of neurodegenerative disorders.

MAP7D2 has also been shown to be involved in the regulation of cancer. It is involved in the production of reactive oxygen species, which can contribute to the development and progression of cancer. It is also involved in the regulation of cellular signaling pathways, which can contribute to the maintenance of cancer cell proliferation.

MAP7D2 is a potential drug target and biomarker for various diseases, including neurodegenerative disorders, cancer, and aging. It is involved in the regulation of cellular homeostasis, signaling pathways, and cellular processes that are critical for the proper functioning of the cell. It is also involved in the production of reactive oxygen species, which can cause damage to cellular components and contribute to various diseases. Therefore, it is a promising target for the development of new therapies for these diseases.

In conclusion, MAP7D2 is a transmembrane protein that plays a crucial role in the regulation of cellular homeostasis, signaling pathways, and cellular processes that are critical for

Protein Name: MAP7 Domain Containing 2

The "MAP7D2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAP7D2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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