MAP7: A Key Player in Microtubule Regulation (G9053)

Target Name: MAP7

NCBI ID: G9053

MAP7

MAP7: A Key Player in Microtubule Regulation

MAP7, also known as dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP-115)), is a protein that is expressed in a variety of tissues and cells throughout the body. It is a key player in the regulation of microtubules, which are dynamic organelles that play a critical role in cell division, transport, and signaling.

MAP7 is a member of the EMAP family of proteins, which are known for their ability to interact with microtubules. EMAP proteins have been implicated in a wide range of cellular processes, including cell division, migration, and the regulation of intracellular signaling pathways.

One of the key functions of MAP7 is its role in the regulation of microtubule dynamics. Microtubules are dynamic organelles that play a critical role in the regulation of cell division, intracellular transport, and signaling. They are composed of a protein core and a series of Composed of tubulin and associated proteins. Among them, MAP7 is one of the proteins and is thought to be a molecule that controls the assembly and depolymerization of microtubules.

MAP7 affects the assembly and depolymerization of microtubules in multiple ways. For example, studies have shown that MAP7 can bind to the 伪-helical region of microtubules, thereby enhancing microtubule stability. In addition, MAP7 can also bind to the 尾-sheet region of microtubules, thereby inhibiting microtubule depolymerization. These findings indicate that MAP7 plays an important role in the assembly and depolymerization of microtubules.

In addition to its effects on microtubules, MAP7 is involved in many other biological processes. For example, studies have shown that MAP7 can participate in cell cycle progression, which is the basic process of cell growth and division. In addition, MAP7 is also involved in apoptosis, which is a process of cell self-destruction and is essential for maintaining tissue homeostasis.

In addition, MAP7 is also closely related to the occurrence and development of many diseases. For example, studies have shown that MAP7 is associated with neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. These findings suggest that MAP7 plays an important role in the development of neurodegenerative diseases and, therefore, may be a potential drug target or biomarker.

MAP7 is a molecule worthy of further study. Future studies can delve into the role of MAP7 in microtubule assembly and depolymerization, as well as its relationship to disease. Additionally, new methods can be developed to detect MAP7 to better understand its role in biology.

Protein Name: Microtubule Associated Protein 7

Functions: Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments

The "MAP7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAP7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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