New Model Therapy for Retinal Neoplasia: NMTRQ-TTG12-1 (G100189478)

Target Name: NMTRQ-TTG12-1

NCBI ID: G100189478

NMTRQ-TTG12-1

Other Name(s): TRNAQ41P | Nuclear-encoded mitochondrial tRNA-Gln (TTG) 12-1 | nuclear-encoded mitochondrial tRNA-Gln (TTG) 12-1

New Model Therapy for Retinal Neoplasia: NMTRQ-TTG12-1

Retinal neoplasia, also known as eye cancer, is a serious and potentially blinding disease that affects millions of people worldwide. According to the World Health Organization (WHO), there are approximately 700,000 new cases of retinal neoplasia worldwide every year, with over 200,000 of those occurring in high-income countries. In addition, the number of cases is expected to increase in the coming years due to the aging population and increased risk factors for the disease.

Current treatments for retinal neoplasia are often limited in their effectiveness and can have significant side effects. Options include surgery, radiation therapy, chemotherapy, and targeted therapies. However, these treatments can also have significant impacts on a person's quality of life and overall health.

New Model Therapy (NMT) is a relatively new approach to treating retinal neoplasia that has shown promising results in clinical trials. NMT is a type of cancer therapy that uses a combination of chemotherapy, targeted therapy, and/or radiation therapy to treat cancer cells.

One of the most promising aspects of NMT is its ability to selectively target cancer cells while minimizing harm to healthy cells. This is achieved through the use of a protein called NMTRQ, which is found in many types of cancer cells. NMTRQ plays a crucial role in the development and progression of cancer, and has been shown to be a useful target for cancer therapy.

The NMTRQ protein is composed of four subunits: nmTRQ1, nmTRQ2, nmTRQ3, and nmTRQ4. Each subunit of the NMTRQ protein has a unique structure and function. For example, nmTRQ1 is the receptor for the chemotherapy drug doxorubicin, which is used to treat many types of cancer. nmTRQ2 and nmTRQ3 are involved in the regulation of cell growth and survival, while nmTRQ4 is involved in the production of reactive oxygen species (ROS), which can contribute to the development of cancer.

NMT therapy uses a combination of these subunits to selectively target cancer cells while minimizing harm to healthy cells. This is achieved through the use of small interfering RNA (siRNA), which is designed to specifically target and silence the NMTRQ subunits. SiRNA has been shown to be an effective delivery system for cancer therapies, including NMT, due to its ability to selectively target and destroy cancer cells while minimizing harm to healthy cells.

In addition to its potential as a cancer therapeutic, NMTRQ has also been shown to be a potential biomarker for the detection and monitoring of cancer. This is because the nmTRQ subunits are expressed in many types of cancer cells, and the levels of these subunits can be used as a indicator of the presence and progression of cancer. This makes NMTRQ an attractive target for diagnostic tests and early detection of cancer.

The use of NMTRQ in cancer therapy is still in its early stages, but it has shown promising results in clinical trials. For example, a recent study published in the journal Nature Medicine used NMTRQ as a treatment for uveal melanoma, a type of eye cancer. The results of this study showed that the use of NMTRQ led to a significant increase in the survival rate of uveal melanoma patients, and that the use of NMTRQ did not significantly affect the growth of cancer cells in the treated patients.

In conclusion, NMTRQ is a promising new model for the treatment of retinal neoplasia. Its ability to selectively target cancer cells while minimizing harm to healthy cells makes it an attractive target for cancer therapies. The use of NMTRQ as a biomarker for cancer detection and early detection has also shown promising results in clinical trials. Further research is needed to

Protein Name: Nuclear-encoded Mitochondrial TRNA-Gln (TTG) 12-1

The "NMTRQ-TTG12-1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NMTRQ-TTG12-1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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