NMRK2: A Potential Drug Target and Biomarker (G27231)

Target Name: NMRK2

NCBI ID: G27231

NMRK2

NMRK2: A Potential Drug Target and Biomarker

NMRK2, also known as MGC126624, is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer. The gene is located on chromosome 16 and encodes for a protein known as nuclear magnetic resonance (NMR) kinase 2.

NMRK2 is a non-coding RNA molecule that plays a critical role in the regulation of gene expression and cell signaling. It is a key regulator of the myeloid/lymphoid gene (MLP) gene, which is responsible for the production of memory cells and the development of the immune system.

Studies have shown that NMRK2 plays a crucial role in the development and progression of various diseases, including cancer. For example, research has shown that high levels of NMRK2 are associated with poor prognosis in patients with pancreatic cancer, and that inhibiting NMRK2 may be a promising strategy for treating this disease.

In addition to its role in cancer, NMRK2 has also been shown to be involved in a variety of other biological processes, including cell signaling, stem cell maintenance, and tissue repair. It is also involved in the regulation of inflammation and has been shown to play a role in the development of autoimmune diseases.

Despite the potential for NMRK2 as a drug target and biomarker, much more research is needed to fully understand its functions and the potential benefits of targeting it. Researchers are currently studying the effects of inhibiting NMRK2 in various experimental models, including cell cultures and animal models, in order to determine its potential effectiveness as a drug.

In addition to its potential as a drug target, NMRK2 has also been shown to be a potential biomarker for several diseases. For example, it has been shown to be elevated in the blood of patients with pancreatic cancer, and may be a useful diagnostic marker for this disease. It has also been shown to be elevated in the urine of patients with urologic cancer, which may be a useful biomarker for this disease.

Overall, NMRK2 is a gene that has the potential to be a drug target and biomarker for a variety of diseases. Further research is needed to fully understand its functions and the potential benefits of targeting it.

Protein Name: Nicotinamide Riboside Kinase 2

Functions: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis

The "NMRK2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NMRK2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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