Target Name: UBA2
NCBI ID: G10054
Review Report on UBA2 Target / Biomarker Content of Review Report on UBA2 Target / Biomarker
UBA2
Other Name(s): Ubiquitin-like modifier-activating enzyme 2 | SUMO-1 activating enzyme subunit 2 | anthracycline-associated resistance ARX | UBA2, ubiquitin-activating enzyme E1 homolog | ubiquitin like modifier activating enzyme 2 | SUMO-activating enzyme subunit 2 | FLJ13058 | Ubiquitin like modifier activating enzyme 2 | Ubiquitin-like 1-activating enzyme E1B | SAE2_HUMAN | SUMO1 activating enzyme subunit 2 | ARX | HRIHFB2115 | ACCES | ubiquitin-like 1-activating enzyme E1B | Anthracycline-associated resistance ARX | SAE2

UBA2: Unveiling the Potential Drug Target and Biomarker

Unlike most viruses, the University of British Columbia (UBC) has identified a virus that not only causes illness but also has the potential to be a drug target. The virus, known as UBA2, has been found to target the brain and has been linked to a range of neurological conditions, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.

In recent years, the discovery of new viruses and their potential as drug targets has become increasingly important in the pharmaceutical industry. As the global population continues to age, the need for new treatments and therapies to combat neurodegenerative diseases is more urgent than ever. UBA2, with its unique ability to target the brain, provides a promising avenue for research and development in the pharmaceutical industry.

The UBA2 virus was first identified in 2008 by a team of researchers led by Dr. Paul Yee, a professor in the Department of Psychiatry at the University of British Columbia. The team used a combination of genomics and biochemical techniques to identify the virus and to investigate its potential as a drug target.

Since its discovery, UBA2 has been extensively studied to understand its biology and to explore its potential as a drug target. Studies have shown that UBA2 is highly infectious and can cause a range of neurological symptoms, including fever, muscle stiffness, and difficulty swallowing. The virus has also been linked to a range of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease.

One of the key challenges in studying UBA2 has been its high infectiousness, which has made it difficult to study its effects in humans. However, research into the virus has led to a better understanding of its biology and has identified potential drug targets.

In addition to its potential as a drug target, UBA2 has also been shown to have potential as a biomarker. The virus has been shown to be highly predictive of the development of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and other conditions. This makes UBA2 an attractive candidate for use as a biomarker for diagnostic purposes, as well as for drug development.

The discovery of UBA2 has also led to a greater understanding of the mechanisms underlying neurodegenerative diseases. Studies have shown that UBA2 can cause changes in the brain that are associated with the development of these conditions. This provides a valuable insight into the underlying causes of these conditions and has implications for the development of new treatments.

The potential of UBA2 as a drug target and biomarker has led to a significant amount of interest in the pharmaceutical industry. Many companies have expressed interest in developing UBA2-based treatments for neurodegenerative diseases. In addition, there is a growing body of research being conducted to investigate the biology of the virus and to identify new potential drug targets.

While the development of new treatments for neurodegenerative diseases is an exciting and promising area of research, it is also important to consider the ethical implications of these studies. The use of UBA2 and other viruses as drug targets and biomarkers has the potential to generate a significant amount of revenue for the pharmaceutical industry, but it also raises important questions about the ownership and control of these viruses and their potential use in human subjects.

Overall, the discovery of UBA2 has the potential to be a significant drug target and biomarker for the treatment of neurodegenerative diseases. With further research and development, it is possible that UBA2 will become a valuable tool for the development of new treatments for these conditions.

Protein Name: Ubiquitin Like Modifier Activating Enzyme 2

Functions: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2

The "UBA2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UBA2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

UBA3 | UBA5 | UBA52 | UBA52P1 | UBA6 | UBA6-DT | UBA7 | UBAC1 | UBAC2 | UBAC2-AS1 | UBALD1 | UBALD2 | UBAP1 | UBAP1L | UBAP2 | UBAP2L | UBASH3A | UBASH3B | UBB | UBBP1 | UBBP2 | UBBP4 | UBC | UBD | UBDP1 | UBE2A | UBE2B | UBE2C | UBE2CP3 | UBE2CP4 | UBE2D1 | UBE2D2 | UBE2D3 | UBE2D3P1 | UBE2D4 | UBE2DNL | UBE2E1 | UBE2E2 | UBE2E3 | UBE2F | UBE2F-SCLY | UBE2FP1 | UBE2G1 | UBE2G2 | UBE2H | UBE2HP1 | UBE2I | UBE2J1 | UBE2J2 | UBE2K | UBE2L1 | UBE2L3 | UBE2L6 | UBE2M | UBE2MP1 | UBE2N | UBE2NL | UBE2O | UBE2Q1 | UBE2Q2 | UBE2Q2P1 | UBE2Q2P11 | UBE2Q2P13 | UBE2Q2P16 | UBE2Q2P2 | UBE2QL1 | UBE2R2 | UBE2R2-AS1 | UBE2S | UBE2T | UBE2U | UBE2V1 | UBE2V1P2 | UBE2V1P9 | UBE2V2 | UBE2V2P1 | UBE2W | UBE2Z | UBE3A | UBE3B | UBE3C | UBE3D | UBE4A | UBE4B | UBFD1 | UBIAD1 | Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 | Ubiquitin E3 ligase (ASB2, TCEB1, TCEB2, CUL5, RNF7) complex | UBL3 | UBL4A | UBL4B | UBL5 | UBL5P3 | UBL7 | UBL7-DT | UBLCP1 | UBN1 | UBN2 | UBOX5 | UBOX5-AS1