KRTAP3-3: A Potential Drug Target and Biomarker (G85293)

Target Name: KRTAP3-3

NCBI ID: G85293

KRTAP3-3

KRTAP3-3: A Potential Drug Target and Biomarker

Keratin-associated protein 3-3 (KRTAP3-3) is a protein that is expressed in a variety of tissues, including hair, skin, and nails. It is a member of the keratin gene family, which is responsible for the production of the protein keratin, which is a component of hair, skin, and nails. KRTAP3-3 has been shown to play a role in the regulation of cell growth, differentiation, and survival.

Recent studies have suggested that KRTAP3-3 may have potential as a drug target or biomarker. For example, KRTAP3-3 has been shown to be involved in the development and progression of various diseases, including cancer. Additionally, KRTAP3-3 has been shown to be involved in the regulation of skin texture and pigmentation, which can be useful as a biomarker for skin health.

One potential mechanism by which KRTAP3-3 may be involved in the development and progression of cancer is by contributing to the regulation of cell growth and survival. For example, studies have shown that KRTAP3-3 can be involved in the regulation of cell cycle progression and the execution of cell division. Additionally, KRTAP3-3 has been shown to play a role in the regulation of apoptosis, which is the process by which cells undergo programmed cell death.

Another potential mechanism by which KRTAP3-3 may be involved in the development and progression of cancer is by contributing to the regulation of angiogenesis, which is the process by which new blood vessels are formed. KRTAP3-3 has been shown to be involved in the regulation of angiogenesis and has been shown to play a role in the development of various diseases, including cancer.

In addition to its potential role in cancer development, KRTAP3-3 has also been suggested as a potential drug target. For example, studies have shown that KRTAP3-3 can be targeted by small molecules and has a predicted binding affinity of 7 nM. Additionally, KRTAP3-3 has been shown to be involved in the regulation of various cellular processes, including cell adhesion, migration, and survival, which could make it a potential target for small molecules with pharmacological activity.

In conclusion, KRTAP3-3 is a protein that has been shown to play a role in a variety of cellular processes, including cell growth, differentiation, and apoptosis. Its potential as a drug target or biomarker makes it an attractive target for further research and may have the potential to contribute to the development of new treatments for a variety of diseases.

Protein Name: Keratin Associated Protein 3-3

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP3-3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP3-3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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