ATP5PO: A Potential Drug Target and Biomarker (G539)

Target Name: ATP5PO

NCBI ID: G539

ATP5PO

ATP5PO: A Potential Drug Target and Biomarker

ATP5PO is a protein that is expressed in various tissues and organs, including the brain, heart, and kidneys. It is a key regulator of the cell signaling pathway known as the cAMP signaling pathway, which plays a crucial role in the regulation of various cellular processes, including inflammation, stress, and cell survival.

Recent studies have identified ATP5PO as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. The cAMP signaling pathway has been implicated in the development and progression of many of these diseases, and blocking the activity of ATP5PO has been shown to have therapeutic effects.

One of the key reasons for the potential of ATP5PO as a drug target is its involvement in the regulation of cellular signaling pathways that are often disrupted in diseases such as cancer and neurodegenerative diseases. For example, studies have shown that the cAMP signaling pathway is often hyperactive in cancer cells, and that inhibiting its activity has the potential to be a therapeutic approach.

In addition to its involvement in cellular signaling pathways, ATP5PO has also been shown to play a role in the regulation of various cellular processes that are important for maintaining tissue homeostasis. For example, it has been shown to regulate the movement of immune cells into the site of inflammation, which is important for controlling infections and autoimmune diseases.

As a potential biomarker, ATP5PO has been shown to be involved in the regulation of various cellular processes that are important for disease diagnosis and prognosis. For example, studies have shown that levels of ATP5PO have been altered in a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

In addition to its potential as a drug target and biomarker, ATP5PO is also of interest as a potential therapeutic approach. Studies have shown that inhibiting the activity of ATP5PO has the potential to be a therapeutic approach for a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

For example, one study shown that inhibiting the activity of ATP5PO using a small molecule inhibitor significantly reduced the growth of cancer cells. Another study showed that inhibiting the activity of ATP5PO using a monoclonal antibody targeting ATP5PO reduced the neurodegeneration caused by a neurotoxin in rat models of Alzheimer's disease.

In conclusion, ATP5PO is a protein that has the potential to be a drug target and biomarker for a variety of diseases. Its involvement in the regulation of cellular signaling pathways and its role in the regulation of cellular processes that are important for tissue homeostasis make it an attractive candidate for therapeutic intervention. Further research is needed to fully understand the potential of ATP5PO as a drug target and biomarker.

Protein Name: ATP Synthase Peripheral Stalk Subunit OSCP

Functions: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements

The "ATP5PO Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ATP5PO comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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