MARCHF5: A Potential Drug Target and Biomarker (G54708)

Target Name: MARCHF5

NCBI ID: G54708

MARCHF5

MARCHF5: A Potential Drug Target and Biomarker

MARCHF5, short for Melanoma- associated protein-5, is a protein that is expressed in high levels in melanoma cells. It is a potential drug target and biomarker for melanoma, which is one of the most aggressive forms of skin cancer.

Melanoma is a type of cancer that develops from melanocytes, the pigment-producing cells in the skin. The most common type of melanoma is melanoma type 2, which is the most deadly form of skin cancer. It can appear in any part of the body, including the face, neck, and arms, and can be highly aggressive.

MARCHF5 is a 22-kDa protein that is expressed in high levels in melanoma cells. It is a member of the PDGF receptor (PDGF) family, which is a group of transmembrane proteins that are involved in cell signaling. PDGF signaling is involved in many cellular processes, including cell growth, differentiation, and survival.

MARCHF5 has been shown to be involved in the development and progression of melanoma. Studies have shown that high levels of MARCHF5 are associated with the development of melanoma, and that inhibiting MARCHF5 may be a promising strategy for treating melanoma.

One of the potential benefits of targeting MARCHF5 is that it is a protein that is expressed in high levels in all types of melanoma, making it a potential biomarker for melanoma. This means that targeting MARCHF5 could be a useful diagnostic tool for melanoma, as well as a potential target for new treatments.

Another potential benefit of targeting MARCHF5 is that it is involved in many cellular processes that are important for cancer growth and progression. By targeting MARCHF5, researchers may be able to disrupt the signaling pathways that are driving the growth and progression of melanoma cells.

Targeting MARCHF5 in melanoma has the potential to be a powerful new treatment for this disease. By disrupting the signaling pathways that are driving the growth and progression of melanoma cells, researchers may be able to inhibit the development and progression of new melanoma tumors.

In conclusion, MARCHF5 is a potential drug target and biomarker for melanoma. Its high expression levels in melanoma cells and its involvement in many cellular processes that are important for cancer growth and progression make it an attractive target for researchers. Further studies are needed to determine the full potential of targeting MARCHF5 in melanoma.

Protein Name: Membrane Associated Ring-CH-type Finger 5

Functions: Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1

The "MARCHF5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MARCHF5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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