Targeting MAS1 Gene Could Be Cancer Drug Target Or Biomarker (G4142)

Target Name: MAS1

NCBI ID: G4142

MAS1

Targeting MAS1 Gene Could Be Cancer Drug Target Or Biomarker

Mutations in the MAS1 gene have been identified as a risk factor for various diseases, including cancer. The MAS1 oncogene has also been shown to promote the growth and survival of cancer cells. Therefore, targeting the MAS1 gene has the potential to be a valuable drug target or biomarker for cancer treatment.

Drug Targets

One of the primary targets of the MAS1 oncogene is the inhibition of its downstream signaling pathways. The MAS1 gene encodes a protein that plays a role in the development and progression of cancer. It is a transcription factor that regulates the expression of target genes, including pro-inflammatory and oncogenic genes.

The MAS1 gene has been shown to promote the growth and survival of cancer cells. It has been shown to inhibit the negative regulatory effects of the tumor suppressor gene, p53, leading to the activation and proliferation of cancer cells. Therefore, inhibiting the MAS1 gene has the potential to be a valuable drug target for cancer treatment.

Biomarkers

Another potential use of the MAS1 gene as a biomarker is its ability to be expressed and detected in various types of cancer. The MAS1 gene has been shown to be expressed in a variety of cancer types, including breast, ovarian, and colorectal cancers. Therefore , the MAS1 gene can be used as a biomarker for the detection and diagnosis of cancer.

Targeting the MAS1 gene has also been shown to be effective in preclinical studies for cancer treatment. In animal models of cancer, inhibitors of the MAS1 gene have been shown to have a beneficial effect on the inhibition of cancer growth and the extension of survival.

Conclusion

In conclusion, the MAS1 oncogene has the potential to be a valuable drug target or biomarker for cancer treatment. Its ability to promote the growth and survival of cancer cells, as well as its expression in a variety of cancer types, makes it an attractive target for inhibition with the goal of treating cancer. Further research is needed to fully understand the effects of targeting the MAS1 gene in cancer treatment.

Protein Name: MAS1 Proto-oncogene, G Protein-coupled Receptor

Functions: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1

The "MAS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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