MATCAP1: A Potential Drug Target Or Biomarker (G653319)

Target Name: MATCAP1

NCBI ID: G653319

MATCAP1

MATCAP1: A Potential Drug Target Or Biomarker

Microtubule-associated tyrosine carboxypeptidase (MATCAP1) is a protein that is expressed in a variety of tissues, including muscle, brain, and heart. It is a member of the superfamily of tyrosine carboxypeptidases and is responsible for the removal of tyrosine carboxylic acids from microtubules. This process is critical for the proper functioning of microtubules, which play a key role in the regulation of cell behavior and mechanical properties. MATCAP1 is also known as tyrosine carboxy-peptidase (TAP), and it is a potential drug target or biomarker in various diseases.

MATCAP1 is a 21-kDa protein that is expressed in a variety of tissues, including muscle, brain, and heart. It is a member of the superfamily of tyrosine carboxypeptidases, which are a group of enzymes that are involved in the removal of carboxylic acids from proteins. These enzymes belong to the trypsin-serine protein family and are characterized by the presence of a specific active site that is responsible for the substitution of a carboxylic acid for a serine residue.

MATCAP1 is found in many different cellular organelles, including mitochondria, endoplasmic reticulum, and various cell types. It is also expressed in various tissues, including muscle, brain, and heart. MATCAP1 is involved in the regulation of microtubule dynamics and is thought to play a key role in the mechanical properties of cells.

One of the functions of MATCAP1 is the removal of tyrosine carboxylic acids from microtubules. This process is critical for the proper functioning of microtubules, which are complex structures that are involved in the regulation of cell behavior and mechanical properties. Microtubules are made up of a series of protein filaments that are held together by interactions between their constituent parts. These filaments are organized in a specific pattern and are involved in the transport of various cellular molecules, including proteins, organelles, and vesicles.

MATCAP1 is also involved in the regulation of the cytoskeleton, which is the structure that gives cells their shape and supports their mechanical properties. The cytoskeleton is made up of a variety of filaments and fibers that are held together by interactions between their constituent parts. MATCAP1 is thought to be involved in the regulation of the stability and dynamics of the cytoskeleton.

In addition to its role in the regulation of microtubules and the cytoskeleton, MATCAP1 is also involved in the regulation of various cellular processes. For example, it is thought to be involved in the regulation of cell growth, cell division, and cell survival. MATCAP1 may also be involved in the regulation of cell signaling, as it has been shown to interact with various signaling proteins.

MATCAP1 is also a potential drug target or biomarker in various diseases. For example, it is a known biomarker for the neurodegenerative disease Alzheimer's disease, as it has been shown to be decreased in the brains of individuals with this disease. MATCAP1 may also be a potential drug target for various other diseases, including cancer, as it has been shown to be involved in the regulation of cellular processes that are involved in the development and progression of these diseases.

In conclusion, MATCAP1 is a protein that is expressed in a variety of tissues and is involved in the regulation of microtubule dynamics and the cytoskeleton. It is a potential drug target or biomarker in various diseases and may be a useful target for the development of new therapies. Further research is needed to fully understand the role of MATCAP1 in

Protein Name: Microtubule Associated Tyrosine Carboxypeptidase 1

Functions: Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:35482892). Also able to remove the C-terminal phenylalanine residue of alpha-tubulin TUBA8 (PubMed:35482892). Recognizes adjacent tubulin dimers along the same protofilament (PubMed:35482892)

The "MATCAP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MATCAP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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