MAS1L: A Potential Drug Target and Biomarker (G116511)

Target Name: MAS1L

NCBI ID: G116511

MAS1L

MAS1L: A Potential Drug Target and Biomarker

MAS1L (MAS-R), a protein encoded by the MAS gene, is a key regulator of the cell cycle and has been implicated in various cellular processes, including cell growth, differentiation, and response to stimuli. The MAS gene has four splice variants, MAS1, MAS2, MAS3, and MAS4, each of which encodes a different isoform of the MAS protein. MAS1L, encoded by the MAS1 splice variant, is a 21-kDa protein that plays a critical role in regulating the cell cycle and has been suggested as a potential drug target and biomarker.

The MAS gene is located on chromosome 18q21 and has been implicated in various cellular processes, including cell growth, differentiation, and response to stimuli. MAS1L is a 21-kDa protein that is expressed in various tissues and cells, including liver, lung, and pancreatic cancer. MAS1L has been shown to play a critical role in regulating the cell cycle by preventing the metaphosphorylation of mitochondrial serine residues, which is a critical step in the G1 phase of the cell cycle. MAS1L also interacts with the protein p21, which is a negative regulator of the T-cell receptor.

MAS1L has been shown to have various functions, including regulating cell growth, cell cycle progression, and apoptosis. For example, MAS1L has been shown to promote the growth of various cancer cell lines, including liver cancer (3) and pancreatic cancer. MAS1L has also been shown to contribute to the development of various types of cancer, including lung cancer (5) and colorectal cancer.

In addition to its role in cell growth and the cell cycle, MAS1L has also been shown to play a critical role in the regulation of cellular apoptosis. MAS1L has been shown to interact with the protein Bcl-2, which is a protein that can prevent apoptosis. MAS1L has also been shown to regulate the expression of the genes p53 and p21, which are involved in the regulation of apoptosis.

MAS1L has also been shown to have various potential therapeutic applications. For example, MAS1L has been shown to be a potential drug target by inhibiting its activity in cell experiments and in animal models of cancer. In addition, MAS1L has also been shown to be a potential biomarker for various types of cancer, including pancreatic cancer.

In conclusion, MAS1L is a protein that has been shown to play a critical role in regulating the cell cycle and has been implicated in various cellular processes, including cell growth, differentiation, and response to stimuli. The MAS gene has four splice variants, MAS1, MAS2, MAS3, and MAS4, each of which encodes a different isoform of the MAS protein. MAS1L, encoded by the MAS1 splice variant, is a 21-kDa protein that plays a crucial role in regulating the cell cycle and has been suggested as a potential drug target and biomarker. Further research is needed to fully understand the functions of MAS1L and its potential therapeutic applications.

Protein Name: MAS1 Proto-oncogene Like, G Protein-coupled Receptor

The "MAS1L Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAS1L comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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