Target Name: MAT2B
NCBI ID: G27430
Review Report on MAT2B Target / Biomarker Content of Review Report on MAT2B Target / Biomarker
MAT2B
Other Name(s): Methionine adenosyltransferase 2 subunit beta (isoform 2) | Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase | MAT2B_HUMAN | short chain dehydrogenase/reductase family 23E, member 1 | putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase | Short chain dehydrogenase/reductase family 23E, member 1 | Putative protein product of Nbla02999 | Methionine adenosyltransferase 2B, transcript variant 1 | MAT2B variant 2 | MAT II beta | beta regulatory subunit of methionine adenosyltransferase | methionine adenosyltransferase II, beta | Methionine adenosyltransferase II beta | Methionine adenosyltransferase 2 subunit beta (isoform 1) | SDR23E1 | putative protein product of Nbla02999 | TGR | Nbla02999 | Methionine adenosyltransferase 2B, transcript variant 2 | testicular tissue protein Li 118 | Methionine adenosyltransferase 2 subunit beta | MAT-II | methionine adenosyltransferase 2B | Beta regulatory subunit of methionine adenosyltransferase | MAT2B variant 1 | MATIIbeta | dTDP-4-keto-6-deoxy-D-glucose 4-reductase

MAT2B: Potential Drug Target Or Biomarker

MAT2B, or Methionine adenosyltransferase 2 subunit beta (isoform 2), is a protein that is expressed in various tissues throughout the body. It plays a crucial role in the regulation of methionine, a crucial amino acid that is involved in the structure and function of many proteins. MAT2B is also involved in the transfer of adenosyl groups, which are crucial for the proper functioning of proteins.

Recent studies have suggested that MAT2B may be a potential drug target or biomarker for a variety of diseases. This is because MAT2B is involved in the regulation of many important cellular processes, and alterations in its expression or function have been observed in a wide range of diseases.

One of the potential benefits of targeting MAT2B is its involvement in the regulation of protein synthesis. MAT2B is known to play a role in the transfer of adenosyl groups, which are crucial for the initiation of protein synthesis. This means that MAT2B may be a useful target for drugs that are designed to inhibit protein synthesis.

Another potential benefit of targeting MAT2B is its involvement in the regulation of cellular stress responses. MAT2B has been shown to play a role in the regulation of cellular stress responses, and alterations in its expression have been observed in a variety of diseases that are characterized by cellular stress. This suggests that MAT2B may be a useful target for drugs that are designed to promote cellular stress responses or inhibit stress responses.

In addition to its potential role in drug targeting, MAT2B has also been shown to be a potential biomarker for a variety of diseases. For example, MAT2B has been shown to be expressed in a variety of tissues and has been used as a biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Overall, MAT2B is a protein that is involved in a wide range of cellular processes and has been implicated in the regulation of many important cellular processes. As such, it is a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of MAT2B in cellular processes and its potential as a drug target or biomarker.

Protein Name: Methionine Adenosyltransferase 2B

Functions: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511)

The "MAT2B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAT2B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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