NOL4: A Potential Drug Target and Biomarker for Neurological Disorders

Target Name: NOL4

NCBI ID: G8715

NOL4

NOL4: A Potential Drug Target and Biomarker for Neurological Disorders

NOL4, or NOL4 variant 1, is a protein that is expressed in the nervous system and has been identified as a potential drug target or biomarker for various neurological disorders, including Alzheimer's disease, Parkinson's disease, and depression. NOL4 is a scaffold protein that is involved in the regulation of microtubules, which are important for the movement of neurons and the formation of neural circuits.

Studies have shown that NOL4 is involved in the development and progression of neurodegenerative diseases. For example, researchers have found that mice that have been genetically modified to lack NOL4 have reduced anxiety-like behavior and are less likely to develop Alzheimer's disease compared to control mice. Additionally, studies have shown that NOL4 is also involved in the development of Parkinson's disease, and that mice that have been genetically modified to lack NOL4 have reduced symptoms of the disease.

In addition to its potential as a drug target, NOL4 has also been identified as a potential biomarker for neurodegenerative diseases. This is because it is expressed in the brain and can be detected using techniques such as Western blotting or immunofluorescence. By detecting NOL4 in brain tissue, researchers can monitor the progression of neurodegenerative diseases and track the effectiveness of potential treatments.

While further research is needed to fully understand the potential of NOL4 as a drug target and biomarker, it is clear that NOL4 is an important protein that is involved in the regulation of microtubules and the development and progression of neurodegenerative diseases. Further research is needed to fully understand its role and potential as a therapeutic target.

Protein Name: Nucleolar Protein 4

The "NOL4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NOL4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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