Mutations in GOLGA2P2Y Gene Linked To Neurological Disorders (G84559)

Target Name: GOLGA2P2Y

NCBI ID: G84559

GOLGA2P2Y

Other Name(s): GOLGA2LY1 | GOLGA2 pseudogene 2 Y-linked | GOLGA2P2 | GOLGA2LY

Mutations in GOLGA2P2Y Gene Linked To Neurological Disorders

GOLGA2P2Y, also known as GOLGA2LY1, is a protein that is expressed in the brain and is involved in the development and maintenance of synapses, which are the structural and functional connections between neurons in the brain. Mutations in the GOLGA2P2Y gene have been linked to a range of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. As a result, GOLGA2P2Y has emerged as a promising drug target for the development of new treatments for these disorders.

The GOLGA2P2Y gene is located on chromosome 12q34 and encodes a protein that is composed of 215 amino acids. The protein has a molecular weight of 24 kDa and a pre-membrane glycylation of 130 amino acids. GOLGA2P2Y is expressed in the brain and is involved in the development and maintenance of synapses, which are the structural and functional connections between neurons in the brain.

Mutations in the GOLGA2P2Y gene have been linked to a range of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. Studies have shown that individuals with certain genetic mutations, such as those found in the GOLGA2P2Y gene, are at increased risk of developing these disorders.

In addition to its role in the development and maintenance of synapses, GOLGA2P2Y is also involved in the regulation of neurotransmitter release and the modulation of pain perception. Studies have shown that GOLGA2P2Y plays a role in the regulation of dopamine release and that it is involved in the development of drug addiction.

GOLGA2P2Y has also been shown to be involved in the regulation of pain perception. Studies have shown that GOLGA2P2Y is involved in the modulation of pain sensitivity and that it plays a role in the development of chronic pain.

GOLGA2P2Y has also been shown to be involved in the regulation of neurotransmitter release and the modulation of sleep. Studies have shown that GOLGA2P2Y is involved in the regulation of the release of neurotransmitters such as GABA and that it plays a role in the modulation of sleep-wake cycles.

GOLGA2P2Y has also been shown to be involved in the regulation of inflammation and immune response. Studies have shown that GOLGA2P2Y is involved in the regulation of inflammation and that it plays a role in the development of autoimmune disorders.

In conclusion, GOLGA2P2Y is a protein that is involved in the development and maintenance of synapses and is linked to a range of neurological and psychiatric disorders. As a result, GOLGA2P2Y has emerged as a promising drug target for the development of new treatments for these disorders. Further research is needed to fully understand the role of GOLGA2P2Y in the development and maintenance of synapses and to develop effective treatments for individuals with neurological and psychiatric disorders.

Protein Name: GOLGA2 Pseudogene 2 Y-linked

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