GNG2: A Drug Target / Disease Biomarker (G54331)

Target Name: GNG2

NCBI ID: G54331

GNG2

GNG2: A Drug Target / Disease Biomarker

GNG2, also known as G protein-coupled receptor GPR30, is a protein that is expressed in many different tissues in the body. It is a member of the G protein-coupled receptor family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling. GNG2 is one of the most well-studied G protein-coupled receptors, and a number of potential drug targets have been identified in its gene.

GNG2 is a 12-kDa transmembrane protein that is expressed in a variety of tissues, including the brain, heart, lungs, kidneys, and gastrointestinal tract. It is a member of the G protein-coupled receptor family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling. The G protein-coupled receptor family includes over 700 different genes, and it is expressed in many different tissues and organs throughout the body.

GNG2 is involved in a wide range of physiological processes in the body, including sensory perception, neurotransmitter signaling, and cellular signaling. It is involved in the function of many different neural circuits, including those involved in pain perception, anxiety, and other mood regulation. It is also involved in the regulation of cardiovascular function, and has been shown to play a key role in the regulation of heart rate and blood pressure.

Due to its involvement in a wide range of physiological processes, GNG2 has been identified as a potential drug target. Many studies have identified potential drug candidates that can modulate the activity of GNG2, with a focus on compounds that can modulate the activity of the protein in a specific way. These compounds can then be tested for their potential therapeutic benefits in a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular disease.

One of the most promising areas of research surrounding GNG2 is its potential as a drug target for depression. Depression is a common and debilitating mental disorder that affects millions of people around the world, and there is a need for new and effective treatments. GNG2 has been shown to play a key role in the regulation of mood, and many studies have identified potential drug candidates that can modulate the activity of GNG2. These compounds have the potential to treat depression by modulating the activity of GNG2 and improving the function of neural circuits involved in mood regulation.

Another promising area of research surrounding GNG2 is its potential as a drug target for anxiety. Anxiety is a common and debilitating mental disorder that can have a significant impact on a person's quality of life. GNG2 has been shown to play a key role in the regulation of anxiety, and many studies have identified potential drug candidates that can modulate the activity of GNG2. These compounds have the potential to treat anxiety by modulating the activity of GNG2 and improving the function of neural circuits involved in anxiety regulation.

In addition to its potential as a drug target for depression and anxiety, GNG2 is also being studied for its potential role in other physiological processes. For example, GNG2 has been shown to play a key role in the regulation of pain perception, and many studies have identified potential drug candidates that can modulate the activity of GNG2 in this context. These compounds have the potential to treat chronic pain conditions such as osteoarthritis and neuropathic pain.

Overall, GNG2 is a protein that is involved in a wide range of physiological processes and has been identified as a potential drug target for a variety of diseases. The studies on GNG2 are ongoing, and the potential of this protein as a drug target is being increasingly recognized by the scientific community. Further research is needed to fully understand the function of GNG2 and its potential as a drug

Protein Name: G Protein Subunit Gamma 2

Functions: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity)

The "GNG2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GNG2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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