GNG8: A Heterotrimeric Guanine Nucleotide-Binding Protein 3E (G94235)

Target Name: GNG8

NCBI ID: G94235

GNG8

GNG8: A Heterotrimeric Guanine Nucleotide-Binding Protein 3E

Guanine nucleotide-binding proteins (GNPs) are a family of proteins that play a crucial role in various cellular processes, including DNA replication, repair, and checkout. Gnps are composed of three subunits: G1, G2, and G3, which are held together by a disulfide bond. GNG8, a representative member of the Gnps family, has been identified as a potential drug target or biomarker in various diseases, including cancer, neurodegenerative diseases, and metabolic disorders.

GNG8 is a 34-kDa protein that is expressed in various tissues, including brain, heart, liver, and kidney. It is localized to the endoplasmic reticulum (ER) and is predominantly expressed in the cytoplasm. GNG8 is a heterotrimeric protein, which means that it consists of three subunits that are held together by a disulfide bond. The subunits are G1, G2, and G3, which contain unique amino acid residues that give them unique functions.

G1 is the N-terminus subunit and contains a conserved amino acid sequence that is involved in the N-terminal signaling of Gnps. The N-terminus of G1 contains a putative nuclear localization signal (NLS) that is essential for the localization of Gnps to the ER. G2 is the middle subunit and contains a unique amino acid sequence that is involved in the interaction between Gnps and DNA. The unique amino acid sequence in G2 is known as the N-terminal alpha-helix, which is involved in the formation of a specific conformation that allows Gnps to bind to DNA.

G3 is the C-terminus subunit and contains a unique amino acid sequence that is involved in the interaction between Gnps and other proteins. The unique amino acid sequence in G3 is known as the C-terminal alpha-helix, which is involved in the formation of a specific conformation that allows Gnps to interact with other proteins. G3 also contains a conserved amino acid sequence that is involved in the C-terminal signaling of Gnps.

GNG8 has been shown to play a role in various cellular processes, including DNA replication, repair, and checkout. For example, GNG8 has been shown to be involved in the regulation of DNA replication in various organisms. GNG8 has been shown to interact with the protein responsible for the maintenance of DNA replication, called DnaC. The interaction between GNG8 and DnaC suggests that GNG8 may play a role in regulating the replication of DNA in the cell.

GNG8 has also been shown to be involved in the regulation of DNA repair. GNG8 has been shown to interact with the protein responsible for the repair of DNA damage, called NHEJ. The interaction between GNG8 and NHEJ suggests that GNG8 may play a role in regulating the repair of DNA damage in the cell.

GNG8 has also been shown to be involved in the regulation of metabolism. GNG8 has been shown to interact with the protein responsible for the regulation of metabolism, called SIRT1. The interaction between GNG8 and SIRT1 suggests that GNG8 may play a role in regulating metabolism in the cell.

GNG8 has been shown to be involved in various diseases, including cancer, neurodegenerative diseases, and metabolic disorders. For example, GNG8 has been shown to be involved in the development and progression of cancer. GNG8 has been shown to interact with the protein

Protein Name: G Protein Subunit Gamma 8

Functions: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

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