ACACA: A Drug Target / Disease Biomarker (G31)

Target Name: ACACA

NCBI ID: G31

ACACA

ACACA: A Drug Target / Disease Biomarker

ACACA, short for adenosine-conjugated activator of cAMP-protein kinase, is a protein that plays a critical role in cellular signaling. It is a potent activator of the protein cAMP-protein kinase (PKA), which is a key regulator of various cellular processes, including inflammation, stress, and metabolism.

ACACA has been identified as a potential drug target and is a focus of research in the pharmaceutical industry. Its unique mechanism of action, as well as its potential to modulate a wide range of cellular processes, make it an attractive target for drug development.

The science behind ACACA

ACACA was first identified in the 1970s as a protein that was able to induce cAMP production in cells. This effect was shown to be mediated by the interaction between ACACA and the PKA enzyme.

Over the years, researchers have continued to study the mechanism of action of ACACA and its role in cellular signaling. One of the key findings of these studies is that ACACA is not only a direct activator of the PKA enzyme, but also a powerful inhibitor of its activity.

This dual function of ACACA makes it an intriguing target for drug development. By inhibiting the activity of the PKA enzyme, ACACA has been shown to have a variety of potential therapeutic effects, including the inhibition of inflammation, the regulation of stress responses, and the modulation of metabolism.

In addition to its potential therapeutic effects, ACACA also has significant potential as a biomarker. Its ability to induce cAMP production in cells makes it a valuable tool for the study of cellular signaling. This ability can be used to study the effects of drugs on cellular signaling, as well as to identify potential biomarkers for a variety of diseases.

The potential of ACACA as a drug target is based on its unique mechanism of action and its potential to modulate a wide range of cellular processes. While further research is needed to fully understand its therapeutic potential, ACACA is a promising target for drug development and the study of cellular signaling.

ACACA as a potential drug target

The potential of ACACA as a drug target is based on its ability to modulate cellular signaling and its potential therapeutic effects. ACACA has been shown to have a variety of potential therapeutic effects, including the inhibition of inflammation, the regulation of stress responses, and the modulation of metabolism.

One of the key features of ACACA that makes it an attractive target for drug development is its ability to inhibit the activity of the PKA enzyme. This interaction between ACACA and the PKA enzyme makes it a powerful inhibitor of the enzyme's activity, and this property is a potential therapeutic asset.

In addition to its ability to inhibit the PKA enzyme, ACACA has also been shown to have a variety of other potential therapeutic effects. For example, it has been shown to be able to regulate the production of pro-inflammatory cytokines, such as TNF-alpha, and to modulate the activity of cellular signaling pathways that are involved in inflammation, stress, and metabolism.

ACACA's potential as a drug target is based on its ability to modulate cellular signaling and its potential therapeutic effects. While further research is needed to fully understand its therapeutic potential, ACACA is a promising target for drug development and the study of cellular signaling.

ACACA as a potential biomarker

The potential of ACACA as a biomarker is based on its ability to induce cAMP production in cells and its potential to regulate cellular signaling pathways. Its ability to regulate the production of cAMP and its interaction with the PKA enzyme make it a valuable tool for the study of cellular signaling.

In addition to its potential as a drug target, ACACA has also been shown to have significant potential as a biomarker. Its ability to regulate the production of cAMP and its interaction with the PKA enzyme make it a valuable tool for the study of cellular signaling and the development of new diagnostic tools.

ACACA's potential as a biomarker is based on its ability to regulate the production of cAMP and its interaction with the PKA enzyme. This property makes it a valuable tool for the study of cellular signaling and the development of new diagnostic tools.

Protein Name: Acetyl-CoA Carboxylase Alpha

Functions: Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20952656, PubMed:20457939, PubMed:29899443). This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA (PubMed:20952656, PubMed:20457939, PubMed:29899443)

The "ACACA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ACACA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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