GSTT4: A Potential Drug Target and Biomarker (G25774)

Target Name: GSTT4

NCBI ID: G25774

GSTT4

GSTT4: A Potential Drug Target and Biomarker

GSTT4 (Glutathione S-transferase theta 4) is a gene that encodes a protein known as GST4 in humans. GST4 is a member of the GST family of enzymes, which are involved in the detoxification and neutralization of toxic substances. GSTT4 is a transcript variant of the GST gene, which has been identified as a potential drug target in the context of various diseases, including cancer.

GSTT4 is expressed in most tissues of the body and is involved in the detoxification of a wide variety of compounds, including drugs, toxins, and environmental pollutants. GSTT4 is also involved in the regulation of cellular processes, including cell signaling, DNA replication, and stress response.

Studies have suggested that GSTT4 may be involved in the development and progression of certain diseases, including cancer. For example, GSTT4 has been shown to be highly expressed in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, GSTT4 has been associated with poor prognosis in patients with various types of cancer.

GSTT4 has also been shown to be involved in the regulation of cellular processes that are important for cancer progression. For example, GSTT4 has been shown to play a role in the regulation of cell proliferation, apoptosis (programmed cell death), and angiogenesis (the formation of new blood vessels).

In addition to its involvement in cancer, GSTT4 has also been suggested to be involved in a variety of other diseases and conditions, including autoimmune disorders, neurodegenerative diseases, and respiratory diseases.

GSTT4 has also been identified as a potential biomarker for several diseases, including cancer. For example, GSTT4 has been shown to be highly expressed in various types of cancer and has been used as a biomarker for cancer diagnosis and treatment.

In addition to its potential as a drug target and biomarker, GSTT4 is also of interest from a fundamental biological perspective. GSTT4 is a member of the GST family of enzymes, which are characterized by their ability to transfer a gamma glutamyl group from a cysteine residue to a serine residue. This transfer of a gamma glutamyl group is a hallmark of the GST family and is involved in the detoxification and neutralization of a wide variety of substances.

GSTT4 is also involved in the regulation of cellular processes that are important for the function of many different cell types. For example, GSTT4 has been shown to play a role in the regulation of cell signaling, DNA replication, and stress response.

Overall, GSTT4 is a protein that has significant involvement in a variety of cellular processes and has been associated with the development and progression of certain diseases, including cancer. As a result, GSTT4 has generated a great deal of interest as a potential drug target and biomarker. Further research is needed to fully understand the role of GSTT4 in these processes and to develop effective treatments for diseases in which it is involved.

Protein Name: Glutathione S-transferase Theta 4

Functions: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles

The "GSTT4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSTT4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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