Target Name: PHB1P8
NCBI ID: G100418804
Review Report on PHB1P8 Target / Biomarker Content of Review Report on PHB1P8 Target / Biomarker
PHB1P8
Other Name(s): PHBP8 | Prohibitin pseudogene 8 | PHB1 pseudogene 8

PHB1P8: A Drug Target / Disease Biomarker

PHB1P8, also known as 尾-actinin-1 (BA1), is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is a member of the actinin family, which is characterized by the presence of a unique transmembrane domain and a cytoplasmic tail.

PHB1P8 has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. One of the most promising aspects of PHB1P8 is its ability to interact with various signaling pathways, including the TGF-β pathway.

The TGF-β pathway is a well-established signaling pathway that plays a critical role in cell growth, differentiation, and survival. It is involved in the regulation of cell proliferation, cell survival, and the formation of tissues and organs during development. The TGF-β pathway is also involved in the regulation of cell migration, which is critical for the formation of tissues and organs during development and for the maintenance of tissue homeostasis.

PHB1P8 has been shown to play a role in the regulation of TGF-β signaling pathway. It has been shown to interact with the TGF-β receptor, which is a transmembrane protein that is involved in the regulation of TGF-β signaling pathway. The interaction between PHB1P8 and TGF-β receptor has been shown to play a critical role in the regulation of cellular processes, including cell growth, differentiation, and survival.

In addition to its involvement in the TGF-β pathway, PHB1P8 has also been shown to interact with several other signaling pathways, including the PI3K/Akt signaling pathway and the NF-kappa-B signaling pathway. The PI3K/Akt signaling pathway is involved in the regulation of cell survival and the formation of tissues and organs during development, while the NF-kappa-B signaling pathway is involved in the regulation of inflammation and cellular signaling.

The unique structure of PHB1P8, including its cytoplasmic tail and the presence of a unique transmembrane domain, makes it an attractive target for drug development. The cytoplasmic tail of PHB1P8 allows it to interact with the TGF-β receptor and other signaling pathways, while the transmembrane domain allows it to interact with other proteins that are involved in the regulation of cellular processes.

PHB1P8 has also been shown to play a role in the regulation of cellular signaling pathways that are involved in the development and maintenance of tissues and organs. For example, it has been shown to play a role in the regulation of cell proliferation and the formation of the nervous system during development.

In conclusion, PHB1P8 is a protein that has been shown to play a role in various cellular processes that are involved in the development and maintenance of tissues and organs. Its unique structure, including its cytoplasmic tail and transmembrane domain, makes it an attractive target for drug development. Further research is needed to fully understand the role of PHB1P8 in cellular processes and its potential as a drug target.

Protein Name: PHB1 Pseudogene 8

The "PHB1P8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHB1P8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PHB1P9 | PHB2 | PHC1 | PHC1P1 | PHC2 | PHC2-AS1 | PHC3 | Phenylalanyl-tRNA synthetase | PHETA1 | PHETA2 | PHEX | PHEX-AS1 | PHF1 | PHF10 | PHF11 | PHF12 | PHF13 | PHF14 | PHF19 | PHF2 | PHF2-ARID5B complex | PHF20 | PHF20L1 | PHF21A | PHF21B | PHF23 | PHF24 | PHF2P1 | PHF2P2 | PHF3 | PHF5A | PHF6 | PHF7 | PHF8 | PHGDH | PHGR1 | PHIP | PHKA1 | PHKA1-AS1 | PHKA2 | PHKA2-AS1 | PHKB | PHKG1 | PHKG2 | PHLDA1 | PHLDA2 | PHLDA3 | PHLDB1 | PHLDB2 | PHLDB3 | PHLPP1 | PHLPP2 | Phosphatidylinositol 3-kinase (PI3K) | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16 | PI3 | PI4K2A | PI4K2B | PI4KA | PI4KAP1 | PI4KAP2 | PI4KB | PIANP | PIAS1 | PIAS2 | PIAS3