KRTAP6-3: A Potential Drug Target and Biomarker (G337968)

Target Name: KRTAP6-3

NCBI ID: G337968

KRTAP6-3

Other Name(s): Keratin associated protein 6-3 | KRA63_HUMAN | keratin associated protein 6-3 | KAP6.3 | Keratin-associated protein 6-3

KRTAP6-3: A Potential Drug Target and Biomarker

Keratin associated protein 6-3 (KRTAP6-3) is a protein that has been identified as a potential drug target and biomarker in the field of skin diseases. KRTAP6-3 is a 21-kDa protein that is expressed in various tissues, including skin, hair, and nails. It is highly expressed in seborrheic keratitis, a common skin disease that affects millions of people worldwide.

The exact function of KRTAP6-3 is not yet fully understood, but it is known to be involved in the regulation of cell growth, differentiation, and survival. It has been shown to play a role in the development and progression of various skin diseases, including seborrheic keratitis.

One of the key reasons for the potential drug target status of KRTAP6-3 is its role in the development of skin cancer. Studies have shown that KRTAP6-3 is highly expressed in skin cancer tissues, and that it is involved in the regulation of cell proliferation and survival. This suggests that KRTAP6-3 may be a useful target for drugs that are designed to inhibit its function in skin cancer.

In addition to its potential role in skin cancer development, KRTAP6-3 has also been shown to be involved in the regulation of skin inflammation. Studies have shown that KRTAP6-3 is highly expressed in inflammatory skin tissues, and that it is involved in the regulation of inflammation response. This suggests that KRTAP6-3 may be a useful target for drugs that are designed to inhibit its function in skin inflammation.

Another potential drug target for KRTAP6-3 is its role in the regulation of skin texture and pigmentation. Studies have shown that KRTAP6-3 is involved in the regulation of skin texture and pigmentation, and that it plays a role in the development of various skin diseases, including melasma. This suggests that KRTAP6-3 may be a useful target for drugs that are designed to inhibit its function in skin texture and pigmentation.

In conclusion, KRTAP6-3 is a protein that has been identified as a potential drug target and biomarker in the field of skin diseases. Its role in the regulation of cell growth, differentiation, and survival, as well as its involvement in the regulation of skin cancer, inflammation, and texture and pigmentation, make it an attractive target for drug development. Further research is needed to fully understand the function of KRTAP6-3 and its potential as a drug target.

Protein Name: Keratin Associated Protein 6-3

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP6-3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP6-3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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